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. 2023 Nov 6;15(1):225.
doi: 10.1186/s13098-023-01154-2.

Use of digital retinography to detect vascular changes in pre-diabetic patients: a cross-sectional study

Levimar Rocha Araújo  1 , Juliana Lambert Orefice  2 , Monica Aramuni Gonçalves  3 , Nathalia Sernizon Guimarães  1 , Aleida Nazareth Soares  4 , Tassila Salomon  1 , Alessandra Hubner de Souza  5
Affiliations

Use of digital retinography to detect vascular changes in pre-diabetic patients: a cross-sectional study

Levimar Rocha Araújo et al. Diabetol Metab Syndr. .

Abstract

Background: Diabetic retinopathy (DR) is a common complication of DM and may go unnoticed until irreversible damage occurs. Its screening can contribute to the early detection. Although, there are no studies which investigate the ability of digital retinography to detect vascular changes in pre-diabetic patients.

Objective: Identify the prevalence and severity of RD in patients with pre-diabetes.

Methods: Cross-sectionalstudy carried out in a sample of patients with pre-diabetes and weight excess characterized from January 2020 to April 2023. Sociodemographic and clinical variables were collected, in addition to lifestyle habits. Retinographic evaluation was also performed using a Digital Retinography. For the analysis of all variables, the adopted significance level was 5%. The software used for the analysis was SPSS version 25.0.

Results: Of 108 patients selected 7.1% have alteration in the exam indicating DR. Among the participants with diabetic retinopathy, four had the moderate form (50%), three the moderate form (37%) and only one participant had the severe form (13%).

Conclusions: Our findings highlight the importance of preventive measures and adequate control of these conditions in pre-diabetic patients, in order to prevent or delay the progression of diabetic retinopathy and, consequently, reduce the risk of blindness and other ocular complications.

Keywords: Diabetes mellitus; Digital photograph; Obesity; Ophthalmological diagnostic techniques; Pre-diabetes; Type 2 diabetes mellitus; Vascular changes.

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Conflict of interest statement

The authors have no competing interest to declare.

Figures

Fig. 1
Fig. 1
Result of digital retinography and the severity of diabetic retinopathy
See this image and copyright information in PMC

References

    1. Huang Y, Cai X, Mai W, Li M, Hu Y. Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis. BMJ. 2016;355:i5953. doi: 10.1136/bmj.i5953. - DOI - PMC - PubMed
    1. Richter B, Hemmingsen B, Metzendorf MI, Takwoingi Y. Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia. Cochrane Database Syst Rev. 2018;10(10):Cd012661. - PMC - PubMed
    1. Schlesinger S, Neuenschwander M, Barbaresko J, Lang A, Maalmi H, Rathmann W, et al. Prediabetes and risk of mortality, diabetes-related complications and comorbidities: umbrella review of meta-analyses of prospective studies. Diabetologia. 2022;65(2):275–285. doi: 10.1007/s00125-021-05592-3. - DOI - PMC - PubMed
    1. O'Brien MJ, Zhang Y, Bailey SC, Khan SS, Ackermann RT, Ali MK, et al. Screening for prediabetes and diabetes: clinical performance and implications for health equity. Am J Prev Med. 2023;64(6):814–823. doi: 10.1016/j.amepre.2023.01.007. - DOI - PMC - PubMed
    1. Teo ZL, Tham YC, Yu M, Chee ML, Rim TH, Cheung N, et al. Global prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis. Ophthalmology. 2021;128(11):1580–1591. doi: 10.1016/j.ophtha.2021.04.027. - DOI - PubMed

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