Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Nov;176(11):JC127.
doi: 10.7326/J23-0085. Epub 2023 Nov 7.

In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge

KoKo Aung  1 , Thwe Htay  1
Affiliations
Comment

In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge

KoKo Aung et al. Ann Intern Med. 2023 Nov.

Abstract

Copaescu AM, Vogrin S, James F, et al. Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial. JAMA Intern Med. 2023;183:944-952. 37459086.

PubMed Disclaimer

Conflict of interest statement

Disclosures: The commentators have reported no disclosures of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=J23-0085.

Comment on

LinkOut - more resources