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. 2023 Nov 6;195(43):E1475-E1480.
doi: 10.1503/cmaj.230745.

Renal denervation for uncontrolled hypertension

Erez Marcusohn  1 , Sheldon W Tobe  1 , Andrew Dueck  1 , Mina Madan  2
Affiliations

Renal denervation for uncontrolled hypertension

Erez Marcusohn et al. CMAJ. .
No abstract available

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Conflict of interest statement

Competing interests: Sheldon Tobe reports payment from Medtronic Canada. Andrew Dueck reports payment for expert testimony, patents related to magnetic resonance imaging sequences for the evaluation of peripheral plaque. He holds the Maggisano chair in vascular surgery. Mina Madan reports participation on an advisory board for Medtronic Canada. No other competing interests were declared.

Figures

Figure 1:
Figure 1:
Circumferential ablation of renal sympathetic nerves by (A) multielectrode radiofrequency ablation, (B) ultrasound-based denervation or (C) alcohol-mediated perivascular renal denervation. Radiofrequency treatment is delivered bilaterally in a number of locations along the main and extra-parenchymal renal arteries ranging from 3 to 8 mm in diameter. For ultrasound-based or alcohol-mediated denervation, treatment is applied to both main renal arteries only. Note: RDN = renal denervation. Kitty Choi
Figure 2:
Figure 2:
Reduction in mean (A) office systolic blood pressure (BP) and (B) 24-hour ambulatory systolic BP with renal denervation (RDN) versus sham procedure in randomized trials and the Global Symplicity Registry.,– *p < 0.05.
Figure 3:
Figure 3:
Example of a multidisciplinary, team-based care pathway for renal denervation *The clinical specialty of the hypertension experts and interventionalists will vary from centre to centre depending on clinical interests and local expertise. The 2-sided arrows indicate interactions between team members at each level of care. Note: IHTR = interventional hypertension team rounds.
See this image and copyright information in PMC

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