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Review
. 2025 Apr;9(4):445-454.
doi: 10.1038/s41551-023-01115-0. Epub 2023 Nov 6.

A framework for integrating artificial intelligence for clinical care with continuous therapeutic monitoring

Affiliations
Review

A framework for integrating artificial intelligence for clinical care with continuous therapeutic monitoring

Emma Chen et al. Nat Biomed Eng. 2025 Apr.

Abstract

The complex relationships between continuously monitored health signals and therapeutic regimens can be modelled via machine learning. However, the clinical implementation of the models will require changes to clinical workflows. Here we outline ClinAIOps ('clinical artificial-intelligence operations'), a framework that integrates continuous therapeutic monitoring and the development of artificial intelligence (AI) for clinical care. ClinAIOps leverages three feedback loops to enable the patient to make treatment adjustments using AI outputs, the clinician to oversee patient progress with AI assistance, and the AI developer to receive continuous feedback from both the patient and the clinician. We lay out the central challenges and opportunities in the deployment of ClinAIOps by means of examples of its application in the management of blood pressure, diabetes and Parkinson's disease. By enabling more frequent and accurate measurements of a patient's health and more timely adjustments to their treatment, ClinAIOps may substantially improve patient outcomes.

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Conflict of interest statement

Competing interests: The authors declare no competing interests.

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