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Editorial
. 2023 Dec 15;208(12):1259-1261.
doi: 10.1164/rccm.202310-1823ED.

Inhaled NO in COVID-19 Acute Respiratory Distress Syndrome: Yes or No?

Amos Lal  1 , Mark T Gladwin  2 , Ognjen Gajic  1
Affiliations
Editorial

Inhaled NO in COVID-19 Acute Respiratory Distress Syndrome: Yes or No?

Amos Lal et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
The mechanisms of action of inhaled nitric oxide (iNO) in coronavirus disease (COVID-19) acute respiratory distress syndrome (ARDS). ACE2 = angiotensin-converting enzyme 2; IMV = invasive mechanical ventilation; RV = right ventricular; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2.
See this image and copyright information in PMC

Comment on

  • High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure Due to COVID-19: A Multicenter Phase II Trial.
    Di Fenza R, Shetty NS, Gianni S, Parcha V, Giammatteo V, Safaee Fakhr B, Tornberg D, Wall O, Harbut P, Lai PS, Li JZ, Paganoni S, Cenci S, Mueller AL, Houle TT, Akeju O, Bittner EA, Bose S, Scott LK, Carroll RW, Ichinose F, Hedenstierna M, Arora P, Berra L; Nitric Oxide Investigators. Di Fenza R, et al. Am J Respir Crit Care Med. 2023 Dec 15;208(12):1293-1304. doi: 10.1164/rccm.202304-0637OC. Am J Respir Crit Care Med. 2023. PMID: 37774011 Free PMC article. Clinical Trial.

References

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    1. Lal A, Garces JPD, Bansal V, Tekin A, Zec S, Khanna AK, et al. from the Society of Critical Care Medicine Discovery Viral Infection, Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group Pre-hospital aspirin use and patient outcomes in COVID-19: results from the international Viral Infection and Respiratory Illness Universal Study (VIRUS) Arch Bronconeumol . 2022;58:746–753. - PMC - PubMed
    1. Kamenshchikov NO, Berra L, Carroll RW. Therapeutic effects of inhaled nitric oxide therapy in COVID-19 patients. Biomedicines . 2022;10:369. - PMC - PubMed