Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 8;13(1):19407.
doi: 10.1038/s41598-023-44407-w.

Emphatic information on bone mineral loss using quantitative ultrasound sonometer for expeditious prediction of osteoporosis

Affiliations

Emphatic information on bone mineral loss using quantitative ultrasound sonometer for expeditious prediction of osteoporosis

Kottaimalai Ramaraj et al. Sci Rep. .

Abstract

Osteoporosis (OP) and osteoarthritis (OA) are skeletal disorders characterized by a reduction in bone density and quality, resulting in increased fragility and susceptibility to fractures. These illnesses are exhibiting a higher prevalence among both males and females. Fracture risk is determined by using the BMD score (Bone Mineral Density). Looking at the bone loss that comes with osteoarthritis (OA) and osteoporosis (OP), this study also looks at the technological methods used to test for these conditions in order to improve therapies and treatment plans for older people. As a matter of consideration, the prevalence of osteoporosis is higher among postmenopausal women (20%) compared to premenopausal women (14.28%) and males (6.77%). The utilization of a preliminary calcaneal Quantitative Ultrasound (QUS) examination is warranted in order to effectively handle the matter of osteoporosis. The prompt assessment of a patient can provide valuable insights into potential fractures and aid in the prevention of bone injury. In a nutshell, it is imperative to comprehend the impact of OA (osteoarthritis) and OP (osteoporosis) on bone health in order to effectively manage the escalating apprehensions surrounding these conditions. Sophisticated diagnostic techniques, such as the calcaneal quantitative ultrasound (QUS) test, have the potential to enhance the well-being of older individuals by enabling early detection and treatment of many ailments.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Temporal dynamics of bone mass variation across the lifespan*.
Figure 2
Figure 2
Categorization of both genders (all subjects) based on T-score at different ages.
Figure 3
Figure 3
Classifying the disease occurrence in men of various age groups based on T-scores.
Figure 4
Figure 4
Classifying the disease occurrence in premenopausal women of various age groups based on T-scores.
Figure 5
Figure 5
Classifying the disease occurrence in postmenopausal women of various age groups based on T-scores.
Figure 6
Figure 6
Categorization of subjects as per the three cases.
Figure 7
Figure 7
Average T-score of different subjects.

References

    1. Lorentzon M, Johansson H, Harvey NC, Liu E, Vandenput L, McCloskey EV, Kanis JA. Osteoporosis and fractures in women: The burden of disease. Climacteric. 2022;25(1):4–10. doi: 10.1080/13697137.2021.1951206. - DOI - PubMed
    1. Whittier DE, Samelson EJ, Hannan MT, Burt LA, Hanley DA, Biver E, Szulc P, Sornay-Rendu E, Merle B, Chapurlat R, Lespessailles E. Bone microarchitecture phenotypes identified in older adults are associated with different levels of osteoporotic fracture risk. J. Bone Miner. Res. 2022;37(3):428–439. doi: 10.1002/jbmr.4494. - DOI - PMC - PubMed
    1. Ebeling PR, Nguyen HH, Aleksova J, Vincent AJ, Wong P, Milat F. Secondary osteoporosis. Endocr. Rev. 2022;43(2):240–313. doi: 10.1210/endrev/bnab028. - DOI - PubMed
    1. Cooper C, Campion G, Melton L. Hip fractures in the elderly: A world-wide projection. Osteoporos. Int. 1992;2(6):285–289. doi: 10.1007/BF01623184. - DOI - PubMed
    1. Gullberg B, Johnell O, Kanis JA. World-wide projections for hip fracture. Osteoporos. Int. 1997;7(5):407–413. doi: 10.1007/PL00004148. - DOI - PubMed

Publication types