Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 8;18(11):e0286342.
doi: 10.1371/journal.pone.0286342. eCollection 2023.

Funcionality assessed by the core set of the international classification of functionality and health for rheumatoid arthritis: A cohort study

Affiliations

Funcionality assessed by the core set of the international classification of functionality and health for rheumatoid arthritis: A cohort study

Juliana Portes et al. PLoS One. .

Abstract

Objective: The aim of this study was to evaluate the function of a cohort of patients with rheumatoid arthritis (RA) from the core set of the International Classification of Functioning and Health (ICF) for RA over 12 months.

Methods: We used prospective longitudinal data to conduct a cohort study among a well-characterized group of RA patients. Ninety RA patients aged between 40 and 70 years were included in the study. Patients were evaluated at baseline and after 12 months. Age, disease duration, current smoking, erosions, disease activity, functional test, disability and physical activity were evaluated. Then, the ICF core set classification for RA was applied.

Results: 81 patients completed the assessments, the majority of patients were female (88.9%) and the mean age was 56.5 ± 7.3 years. At baseline, the median disease activity was 3.0. There was a statistically significant (p < 0.02) improvement in "Exercise tolerance functions" over 12 months and also a statistically significant (p < 0.001) decrease in "Muscle strength functions" over 12 months. The activity and participation domain showed a weak correlation with the clinical data of the DAS28-PCR (p<0.02).

Conclusion: We conclude that relevant aspects of the ICF Core Set for RA were able to adequately express the physical and functional factors of the RA cohort. This tool provides a common language for the interdisciplinary team, which can enhance the use of timely interventions to prevent physical disability in clinical practice.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flow diagram of the study population.
Fig 2
Fig 2. Change in exercise tolerance functions and power muscle functions over 12 months.

Similar articles

References

    1. Deane K. D.; Demoruelle M. K.; Kelmenson L. B.; Kuhn K. A.; Norris J. M.; Holers V. M. Genetic and environmental risk factors for rheumatoid arthritis. Best Pract Res Clin Rheumatol 2017, 31 (1), 3–18. doi: 10.1016/j.berh.2017.08.003 - DOI - PMC - PubMed
    1. Cruz-Jentoft A. J.; Bahat G.; Bauer J.; Boirie Y.; Bruyère O.; Cederholm T.; et al.. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019, 48 (1), 16–31. doi: 10.1093/ageing/afy169 - DOI - PMC - PubMed
    1. da Mota L. M.; Cruz B. A.; Brenol C. V.; Pereira I. A.; Rezende-Fronza L. S.; Bertolo M. B.; et al.. 2012 Brazilian Society of Rheumatology Consensus for the treatment of rheumatoid arthritis. Rev Bras Reumatol 2012, 52 (2), 152–174. - PubMed
    1. Cruz-Jentoft A. J.; Bahat G.; Bauer J.; Boirie Y.; Bruyère O.; Cederholm T.; et al.. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019. Jul 1;48(4):601. doi: 10.1093/ageing/afz046 - DOI - PMC - PubMed
    1. Roubenoff R.; Roubenoff R. A.; Cannon J. G.; Kehayias J. J.; Zhuang H.; Dawson-Hughes B.; et al.. Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation. J Clin Invest 1994, 93 (6), 2379–2386. doi: 10.1172/JCI117244 - DOI - PMC - PubMed

Publication types