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Review
. 2023 Nov 14;82(20):1953-1966.
doi: 10.1016/j.jacc.2023.08.051.

Imaging Methods for Evaluation of Chronic Aortic Regurgitation in Adults: JACC State-of-the-Art Review

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Free article
Review

Imaging Methods for Evaluation of Chronic Aortic Regurgitation in Adults: JACC State-of-the-Art Review

Lauren S Ranard et al. J Am Coll Cardiol. .
Free article

Abstract

A global multidisciplinary workshop was convened to discuss the multimodality diagnostic evaluation of aortic regurgitation (AR). Specifically, the focus was on assessment tools for AR severity and analyzing evolving data on the optimal timing of aortic valve intervention. The key concepts from this expert panel are summarized as: 1) echocardiography is the primary imaging modality for assessment of AR severity; however, when data is incongruent or incomplete, cardiac magnetic resonance may be helpful; 2) assessment of left ventricular size and function is crucial in determining the timing of intervention; 3) recent evidence suggests current cutpoints for intervention in asymptomatic severe AR patients requires further scrutiny; 4) left ventricular end-systolic volume index has emerged as an additional parameter that has promise in guiding timing of intervention; and 5) the role of additional factors (including global longitudinal strain, regurgitant fraction, and myocardial extracellular volume) is worthy of future investigation.

Keywords: aortic regurgitation; cardiac imaging; valvular heart disease.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Ranard has received institutional funding to Columbia University from Boston Scientific. Dr Bax has received speaker bureau fees from Abbott and Edwards Lifesciences. Dr Delgado has received speaker fees from Abbott Vascular, Edwards Lifesciences, GE Healthcare, Medtronic, Novartis, and Philips; and has received consulting fees from Edwards Lifesciences and Novo Nordisk. Dr Leipsic has received institutional CT core lab contracts with Edwards Lifesciences, Abbott, Boston Scientific, Medtronic, and PI Cardia. Dr Lang is on the Speakers Bureau and has received grants from Philips Medical Systems. Dr Vahl has received institutional funding to Columbia University Irving Medical Center from Boston Scientific, Edwards Lifesciences, JenaValve, Medtronic, and Siemens Healthineers; and has personally received consulting fees from 4C Medical, Abbott Vascular, and Boston Scientific. Dr Leon has received institutional clinical research grants from Abbott, Boston Scientific, Edwards Lifesciences, Medtronic, and JenaValve. Dr Rigolin has stock ownership in Edwards Lifesciences. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

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