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Case Reports
. 2023 Oct 24:14:1216328.
doi: 10.3389/fneur.2023.1216328. eCollection 2023.

Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Hui-Ling Qu  1 , Xiao-Yu Sun  1 , Ying-Jie Dai  1
Affiliations
Case Reports

Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Hui-Ling Qu et al. Front Neurol. .

Abstract

Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent in hyperglycemia was a likely cause of CPM.

Keywords: blood glucose; central pontine myelinolysis; hyperosmolar; hyponatremia; osmotic demyelination syndrome.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Blood glucose level chart.
Figure 2
Figure 2
Central pontine myelinolysis in hyperglycemia.
See this image and copyright information in PMC

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