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Case Reports
. 2023 Nov 6;11(11):e8165.
doi: 10.1002/ccr3.8165. eCollection 2023 Nov.

Fibrodysplasia ossificans progressiva

Chané Smit  1 , André Uys  2
Affiliations
Case Reports

Fibrodysplasia ossificans progressiva

Chané Smit et al. Clin Case Rep. .

Abstract

Key clinical message: Fibrodysplasia ossificans progressiva is a progressively debilitating condition associated with significant morbidity caused by heterotopic ossification. Recognition of the early signs of hallux valgus and painful soft tissue nodules can assist in the early diagnosis of this condition. Periodic radiographic examination is mandatory to monitor the disease progression.

Abstract: Fibrodysplasia ossificans progressiva is a rare condition with an estimated prevalence of one in two million individuals. The condition is characterized by widespread heterotrophic ossification of skeletal muscles and ligaments. We report the case of an 8-year-old female patient and show the radiological progression of the condition.

Keywords: cone‐beam computed tomography; heterotopic ossification.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

FIGURE 1
FIGURE 1
(A) Coronal and (B) axial CBCT images showing calcification of the right medial pterygoid muscle (arrows). (C, D) Three‐dimensional reconstructions and (E) axial CBCT images showed calcification of the rectus capitus muscles (arrows) as well as a decreased space between the cervical vertebrae.
FIGURE 2
FIGURE 2
(A) Posterior–anterior and (B) lateral radiographs of the left leg showing ossification of the vastus lateralis muscle (arrows). Posterior–anterior radiographs of the (C) right and (D) left arm showing calcifications of the bicep muscles and bridging ossification with the lateral chest wall. (E) lateral spine radiograph showing ossifications of the erectus spinae muscles (arrow).
FIGURE 3
FIGURE 3
(A, B) Posterior–anterior chest radiographs when the patient was 2‐year‐old showing ossification in the biceps (inferior arrows in A) and pectoralis major (superior arrows in A and arrow in B) as well as decreased articular spaces between the cervical vertebrae. (C, D) Posterior–anterior chest radiographs when the patient was 6‐year‐old showed progression in the calcifications in the axillae and calcifications adjacent to the spine (erectus spinae).
See this image and copyright information in PMC

References

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