Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Oct 11;15(10):e46850.
doi: 10.7759/cureus.46850. eCollection 2023 Oct.

Managing a Pigmented Corneal Ulcer in a 58-Year-Old Patient

Affiliations
Case Reports

Managing a Pigmented Corneal Ulcer in a 58-Year-Old Patient

Alejandro Acosta et al. Cureus. .

Abstract

We report on a case study involving a 58-year-old male with a pigmented corneal ulcer. The patient presented with a two-month history of an unresolved corneal ulcer in the oculus sinister (OS), accompanied by increasing ocular discomfort. His best corrected visual acuity (BCVA) was 20/20 oculus dexter and hand motion OS. Examination of OS revealed mild conjunctival injection, diffuse corneal edema, and the presence of a central pigmented lesion. Microbiological analysis via culture identified the causative agent as Ochroconis fungi, belonging to the dematiaceous species. Subsequently, the patient's condition was managed through a comprehensive regimen that included multiple topical antifungal agents, a topical antibiotic, and povidone-iodine drops. After two months of treatment, the patient exhibited improvement in his condition. His BCVA improved to counting fingers at a distance of two feet OS.

Keywords: corneal disease; dematiaceous fungi; fungal keratitis; ophthalmology; pigmented corneal ulcer.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. External examination and slit-lamp view of the left eye.
External examination (A) and slit-lamp view (B) of the left eye with fluorescein-highlighted diffuse conjunctival injection and central pigmented keratitis.

References

    1. Pigmented plaque presentation of dematiaceous fungal keratitis: a clinicopathologic correlation. Garg P, Vemuganti GK, Chatarjee S, Gopinathan U, Rao GN. Cornea. 2004;23:571–576. - PubMed
    1. Spectrum of fungal keratitis at Wills Eye Hospital, Philadelphia, Pennsylvania. Tanure MA, Cohen EJ, Sudesh S, Rapuano CJ, Laibson PR. Cornea. 2000;19:307–312. - PubMed
    1. Corneal ulcer caused by Bipolaris hawaiiensis. Anandi V, Suryawanshi NB, Koshi G, Padhye AA, Ajello L. J Med Vet Mycol. 1988;26:301–306. - PubMed
    1. Pigmented corneal ulcer. Yangzes S, Chawla Gupta P, Jha V, Ram J. J Ophthalmic Vis Res. 2019;14:506–508. - PMC - PubMed
    1. Diabetic complications and dysregulated innate immunity. Graves DT, Kayal RA. Front Biosci. 2008;13:1227–1239. - PMC - PubMed

Publication types

LinkOut - more resources