Bioactive Compound-Loaded Nanocarriers for Hair Growth Promotion: Current Status and Future Perspectives
- PMID: 37960095
- PMCID: PMC10649697
- DOI: 10.3390/plants12213739
Bioactive Compound-Loaded Nanocarriers for Hair Growth Promotion: Current Status and Future Perspectives
Abstract
Hair loss (alopecia) has a multitude of causes, and the problem is still poorly defined. For curing alopecia, therapies are available in both natural and synthetic forms; however, natural remedies are gaining popularity due to the multiple effects of complex phytoconstituents on the scalp with fewer side effects. Evidence-based hair growth promotion by some plants has been reported for both traditional and advanced treatment approaches. Nanoarchitectonics may have the ability to evolve in the field of hair- and scalp-altering products and treatments, giving new qualities to hair that can be an effective protective layer or a technique to recover lost hair. This review will provide insights into several plant and herbal formulations that have been reported for the prevention of hair loss and stimulation of new hair growth. This review also focuses on the molecular mechanisms of hair growth/loss, several isolated phytoconstituents with hair growth-promoting properties, patents, in vivo evaluation of hair growth-promoting activity, and recent nanoarchitectonic technologies that have been explored for hair growth.
Keywords: hair growth; molecular mechanisms; nanoarchitectonics technology; nanocarriers; phytoconstituents.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Similar articles
-
Hair Growth: Focus on Herbal Therapeutic Agent.Curr Drug Discov Technol. 2015;12(1):21-42. doi: 10.2174/1570163812666150610115055. Curr Drug Discov Technol. 2015. PMID: 26058803 Review.
-
Natural Compounds Used for Treating Hair Loss.Curr Pharm Des. 2023;29(16):1231-1244. doi: 10.2174/1381612829666230505100147. Curr Pharm Des. 2023. PMID: 37151166 Review.
-
Modulation of Hair Growth Promoting Effect by Natural Products.Pharmaceutics. 2021 Dec 15;13(12):2163. doi: 10.3390/pharmaceutics13122163. Pharmaceutics. 2021. PMID: 34959442 Free PMC article. Review.
-
Childhood Alopecia Areata: An Overview of Treatment and Recent Patents.Recent Pat Inflamm Allergy Drug Discov. 2020;14(2):117-132. doi: 10.2174/1872213X14999200728145822. Recent Pat Inflamm Allergy Drug Discov. 2020. PMID: 32723274 Review.
-
A Comprehensive Review of Natural Alternatives for Treatment of Alopecia with an Overview of Market Products.J Med Food. 2022 Sep;25(9):869-881. doi: 10.1089/jmf.2021.0156. Epub 2022 Jul 7. J Med Food. 2022. PMID: 35796701 Review.
Cited by
-
Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation.Aesthetic Plast Surg. 2025 Aug 11. doi: 10.1007/s00266-025-05077-3. Online ahead of print. Aesthetic Plast Surg. 2025. PMID: 40790388 Review.
-
Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology.Molecules. 2025 Jan 4;30(1):167. doi: 10.3390/molecules30010167. Molecules. 2025. PMID: 39795223 Free PMC article. Review.
-
Enhancing hair regeneration: Recent progress in tailoring nanostructured lipid carriers through surface modification strategies.ADMET DMPK. 2024 Jul 20;12(3):431-462. doi: 10.5599/admet.2376. eCollection 2024. ADMET DMPK. 2024. PMID: 39091900 Free PMC article. Review.
-
Hydrogel forming microneedles loaded with VEGF and Ritlecitinib/polyhydroxyalkanoates nanoparticles for mini-invasive androgenetic alopecia treatment.Bioact Mater. 2024 Apr 23;38:95-108. doi: 10.1016/j.bioactmat.2024.04.020. eCollection 2024 Aug. Bioact Mater. 2024. PMID: 38699241 Free PMC article.
References
-
- Norwood O.T.T. Incidence of female androgenetic alopecia (female pattern alopecia) Dermatol. Surg. 2001;27:53–54. - PubMed
Publication types
LinkOut - more resources
Full Text Sources