Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2024 Feb 10;42(5):571-583.
doi: 10.1200/JCO.23.00339. Epub 2023 Nov 14.

Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial

Joaquin Mateo  1 , Johann S de Bono  2 , Karim Fizazi  3 , Fred Saad  4 , Neal Shore  5 , Shahneen Sandhu  6 , Kim N Chi  7 , Neeraj Agarwal  8 , David Olmos  9 , Antoine Thiery-Vuillemin  10 , Mustafa Özgüroğlu  11 , Niven Mehra  12 , Nobuaki Matsubara  13 , Jae Young Joung  14 , Charles Padua  15 , Ernesto Korbenfeld  16 , Jinyu Kang  17 , Helen Marshall  18 , Zhongwu Lai  19 , Alan Barnicle  20 , Christian Poehlein  21 , Natalia Lukashchuk  20 , Maha Hussain  22
Affiliations
Clinical Trial

Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial

Joaquin Mateo et al. J Clin Oncol. .

Abstract

Olaparib improved PFS and OS across subgroups of BRCA1/2mut #prostatecancer patients in the PROFOUND phase III trial.

Trial registration: ClinicalTrials.gov NCT02987543.

PubMed Disclaimer

Publication types

MeSH terms

Associated data

LinkOut - more resources