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. 2023 Nov 14;10(11):ENEURO.0430-23.2023.
doi: 10.1523/ENEURO.0430-23.2023. Print 2023 Nov.

Brain's Best Kept Secret: Degeneracy

Affiliations

Brain's Best Kept Secret: Degeneracy

Christophe Bernard. eNeuro. .
No abstract available

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Figures

Figure 1.
Figure 1.
Similar model-network activity from different network properties. The pyloric rhythm is produced by a pacemaker network consisting of the anterior burster (AB) neuron, which is electrically coupled to two pyloric dilator (PD) neurons, and of two types of follower neurons: a single lateral pyloric (LP) neuron and five to eight pyloric (PY) neurons. The follower neurons receive inhibitory glutamatergic synapses with fast dynamics from the AB neuron, and inhibitory cholinergic synapses with slow dynamics from the PD neurons. The LP neuron has an inhibitory glutamatergic synapse that feeds back to the PD neurons, and the LP neuron has reciprocal inhibitory glutamatergic connections with at least some of the PY neurons. a, b, Voltage traces from two model pyloric networks. Scale bars: 0.5 s and 50 mV. c, Selected membrane conductances (top) and synaptic conductances of the model network shown in a. d, Selected membrane conductances (top) and synaptic conductances of the model network shown in b. The two networks generated very similar activity despite very different cellular and synaptic properties. Reprinted with permission from Prinz et al. (2004).

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