Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;15(12):3046-3054.
doi: 10.1111/os.13936. Epub 2023 Nov 14.

Advances in the Application of Bone Transport Techniques in the Treatment of Bone Nonunion and Bone Defects

Affiliations
Review

Advances in the Application of Bone Transport Techniques in the Treatment of Bone Nonunion and Bone Defects

Zhenhao Li et al. Orthop Surg. 2023 Dec.

Abstract

Bone nonunion and bone defects frequently occur following high-energy open injuries or debridement surgeries, presenting complex challenges to treatment and significantly affecting patients' quality of life. At present, there are three primary treatment options available for addressing bone nonunion and bone defects: vascularized bone grafts, the Masquelet technique, and the Ilizarov technique. The Ilizarov technique, also known as distraction osteogenesis, is widely favored by orthopedic surgeons because of several advantages, including minimal soft tissue requirements, low infection risk, and short consolidation time. However, in recent years, the application of the Masquelet technique has resulted in novel treatment methods for managing post-traumatic bone infections when bone defects are present. Although these new techniques do not constitute a panacea, they continue to be the most commonly employed options for treating complex large bone nonunion and bone defects. This review evaluates the currently available research on the Ilizarov and Masquelet bone transport techniques applied at various anatomical sites. Additionally, it explores treatment durations and associated complications to establish a theoretical foundation that can guide clinical treatment decisions and surgical procedures for the management of bone nonunion and bone defects.

Keywords: Bone defects; Bone nonunion; Bone transport; Ilizarov technique; Masquelet technique.

PubMed Disclaimer

Conflict of interest statement

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Masquelet technique diagram. (A) Thorough debridement and fixation. (B) Filling with PMMA bone cement. (C) 6–8 weeks after placement of PMMA bone cement, remove the bone cement and membrane induced endograft. (D) Fusion of the grafted bone with the surrounding bone.
FIGURE 2
FIGURE 2
Literature screening flowchart.
FIGURE 3
FIGURE 3
Schematic diagram of Ilizarov technique for tibiofibular fracture. (A) Lower limb tibiofibular fracture with bone discontinuity. (B\C) Ilizarov external fixator stretches and positions the broken end of the bone to a predetermined position by means of wires and braces, stimulating the regenerative potential of the bone tissue by slow and continuous tensile stress. (D) New bone scab formation and tibiofibular fracture healing.

References

    1. Zhang Q, Yin P, Hao M, Li J, Lv H, Li T, et al. Bone transport for the treatment of infected forearm nonunion. Injury. 2014;45:1880–1884. - PubMed
    1. Li J, Li M, Wang W, Li B, Liu L. Evolution and development of Ilizarov technique in the treatment of infected long bone nonunion with or without bone defects. Orthop Surg. 2022;14:824–830. - PMC - PubMed
    1. Yang HQ, Qu L. Ilizarov bone transport technique. Zhongguo Gu Shang. 2022;10:903–907. - PubMed
    1. Swiontkowski MF. Outcome in patients with an infected nonunion of the long bones treated with a reinforced antibiotic bone cement rod. J Orthop Trauma. 2012;2012:43–45. - PubMed
    1. Chen P, Yang DS, Guo QJ, Zhen XZ. Clinical observation of Masquelet technique for treatment of posttraumatic osteomyelitis LING Jian‐sheng. Journal of. Clin Orthop. 2019;22(5):610–612.