DISC1 protein aggregates in cerebrospinal fluid as a potential diagnostic biomarker for first-episode psychosis
- PMID: 37964686
- DOI: 10.1111/pcn.13604
DISC1 protein aggregates in cerebrospinal fluid as a potential diagnostic biomarker for first-episode psychosis
Comment on
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Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.Psychiatry Clin Neurosci. 2023 Dec;77(12):665-671. doi: 10.1111/pcn.13594. Epub 2023 Oct 6. Psychiatry Clin Neurosci. 2023. PMID: 37668563
References
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- Bradshaw NJ, Korth C. Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness. Mol. Psychiatry 2019; 24: 936-951.
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- Pils M, Rutsch J, Eren F et al. Disrupted-in-schizophrenia 1 (DISC1) protein aggregates in cerebrospinal fluid are elevated in first-episode psychosis patients. Psychiatry and Clinical Neurosciences 2023; 77: 665-671. https://doi.org/10.1111/pcn.13594.
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- Hui KK, Endo R, Sawa A, Tanaka M. A perspective on the potential involvement of impaired proteostasis in neuropsychiatric disorders. Biol. Psychiatry 2022; 91: 335-345.
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