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Case Reports
. 2023 Jan-Dec:14:21501319231213744.
doi: 10.1177/21501319231213744.

A Rare Case of Losartan-Induced Visceral Angioedema

Steven Rosas  1 , Austin Fowler  2 , Emily Stodgill  1 , Mark Deyo-Svendsen  1 , Michael Phillips  1
Affiliations
Case Reports

A Rare Case of Losartan-Induced Visceral Angioedema

Steven Rosas et al. J Prim Care Community Health. 2023 Jan-Dec.

Abstract

The following describes a case of isolated visceral angioedema related to an angiotensin II receptor blocker (ARB) medication. Additionally, we discuss the pathophysiology of drug-induced angioedema, various presentations that can be encountered, and the leading theorized mechanisms of how renin-angiotensin-aldosterone system (RAAS) blocking medications lead to angioedema. The goal of sharing this case is to help increase awareness of the possibility of ARB-induced angioedema and to recommend keeping visceral angioedema as part of the differential diagnosis when presented with a patient who is taking an angiotensin converting enzyme inhibitor (ACEI) or ARB medication that is experiencing gastrointestinal symptoms of unclear etiology.

Keywords: adverse drug reaction; angiotensin receptor blockers; intestinal angioedema; losartan; visceral angioedema.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
CT scan with IV contrast images demonstrating thickening and edema of mucosal and submucosal tissues.
See this image and copyright information in PMC

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