Fever and neutropenia in pediatric oncology and stem cell transplant patients: an editorial commentary on updated international clinical practice guidelines
- PMID: 37969121
- PMCID: PMC10644023
- DOI: 10.21037/tp-23-368
Fever and neutropenia in pediatric oncology and stem cell transplant patients: an editorial commentary on updated international clinical practice guidelines
Keywords: Cellular therapies; cell-free DNA; resource-constrained.
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tp.amegroups.com/article/view/10.21037/tp-23-368/coif). AH is supported by the National Institute of Health – National Research Service Award (NIH-NRSA) Research Fellowship in Translational & Genomic Pediatric Cancer Epidemiology (No. T32CA099936). BKT has received grant funding from Merck, the Immune Deficiency Foundation, and the Centers for Disease Control and Prevention; honoraria from Horizon, Seegene, and Sanofi; and travel support from the Doximity Foundation. CLE is a consultant with Elixirgen Therapeutics, Inc. and is supported by the National Institutes of Health’s National Center for Advancing Translational Sciences (NIH NCATS) (Nos. KL2TR002492 and UL1TR002494). The authors have no other conflicts of interest to declare.
Comment on
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Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update.J Clin Oncol. 2023 Mar 20;41(9):1774-1785. doi: 10.1200/JCO.22.02224. Epub 2023 Jan 23. J Clin Oncol. 2023. PMID: 36689694 Free PMC article.
References
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- Kumar A, Biswas B, Chopra A, et al. Early Discontinuation versus Continuation of Antimicrobial Therapy in Low Risk Pediatric Cancer Patients with Febrile Neutropenia, Before Recovery of Counts: A Randomized Controlled Trial (DALFEN Study). Indian J Pediatr 2021;88:240-5. 10.1007/s12098-020-03377-x - DOI - PubMed
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- Santolaya ME, Alvarez AM, Acuña M, et al. Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial. Clin Microbiol Infect 2017;23:173-8. 10.1016/j.cmi.2016.11.001 - DOI - PMC - PubMed
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