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. 2023 Sep-Oct;12(5):435-436.
doi: 10.1097/eus.0000000000000037. Epub 2023 Oct 23.

Pancreatic leiomyosarcoma: EUS findings of an uncommon pancreatic mass (with video)

Marcantonio Gesualdo  1 , Noemi Sara Bertetti  2 , Umberto Mortara  3 , Francesca Maletta  3 , Francesco Moro  4 , Marco Sacco  1 , Mauro Bruno  1 , Claudio Giovanni De Angelis  1 , Silvia Gaia  1
Affiliations

Pancreatic leiomyosarcoma: EUS findings of an uncommon pancreatic mass (with video)

Marcantonio Gesualdo et al. Endosc Ultrasound. 2023 Sep-Oct.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Cytological sample showed spindle cells proliferation with elongated, cigar-shaped and blunt-ended nuclei with severe atypia, variable pleomorphism, and fascicular grown pattern.
Figure 2
Figure 2
Immunohistochemical tests revealed these cells to be diffusely positive for desmin, focally positive for smooth muscle actin, and negative for CD117, DOG1, cytokeratin AE1–3, and S100. MIB1 antibody for Ki67 highlighted a proliferation rate of 10%.
Figure 3
Figure 3
Histological examination of the neoplasm showed spindle-shaped cells with plump, blunt-ended nuclei, fields of nuclear pleomorphism, and distinctly eosinophilic fibrillary cytoplasm. Mitotic figures were common, including atypical ones. The cells merged with blood vessel's wall and were set in long intersecting fascicles. Hyalinized hypocellular areas and tumor necrosis were focally present.
Figure 4
Figure 4
At low magnification, the tumor merges with the blood vessel's wall (arrow), and the tumor borders appear well circumscribed (arrowhead) without invasion of pancreatic parenchyma (*).
See this image and copyright information in PMC

References

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