Determinants of gemcitabine response in pancreatic cancer: are we there?
- PMID: 37969825
- PMCID: PMC10643581
- DOI: 10.21037/jgo-2023-04
Determinants of gemcitabine response in pancreatic cancer: are we there?
Keywords: Pancreatic cancer; RNA; biomarker; gemcitabine.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://jgo.amegroups.com/article/view/10.21037/jgo-2023-04/coif). GMO has received Honoraria/Consulting fees from AstraZeneca, Roche, Servier, MSD, Incyte and Eisai. She has received grant funding from Roche. OMF has no conflicts of interest to report.
Comment on
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Performance of a blood-based RNA signature for gemcitabine-based treatment in metastatic pancreatic adenocarcinoma.J Gastrointest Oncol. 2023 Apr 29;14(2):997-1007. doi: 10.21037/jgo-22-946. Epub 2023 Apr 10. J Gastrointest Oncol. 2023. PMID: 37201091 Free PMC article.
References
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- Wainberg ZA, Melisi D, Macarulla T, et al. NAPOLI-3: A randomized, open-label phase 3 study of liposomal irinotecan + 5-fluorouracil/leucovorin + oxaliplatin (NALIRIFOX) versus nab-paclitaxel + gemcitabine in treatment-naïve patients with metastatic pancreatic ductal adenocarcinoma (mPDAC). J Clin Oncol 2023;41:LBA661. 10.1200/JCO.2023.41.4_suppl.LBA661 - DOI - PMC - PubMed
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