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Comment
. 2023 Dec 1;51(12):e283-e284.
doi: 10.1097/CCM.0000000000006054. Epub 2023 Nov 16.

The authors reply

Federico Angriman  1   2   3   4   5 , Fiona Muttalib  4 , François Lamontagne  5 , Neill K J Adhikari  1   2   3   4   5 ; LOVIT Investigators
Collaborators, Affiliations
Comment

The authors reply

Federico Angriman et al. Crit Care Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Dr. Lamontagne’s institution received funding from the Lotte & John Hecht Memorial Foundation. The remaining authors have disclosed that they do not have any potential conflicts of interest.

Comment on

References

    1. Plummer MP, Lankadeva YR, Bellomo R, et al.: Apples and Oranges—All ‘Vitamin C’ May Not Be Created Equal. Crit Care Med. 2023; 51:e281–e282
    1. Lamontagne F, Masse M-H, Menard J, et al.; LOVIT Investigators and the Canadian Critical Care Trials Group: Intravenous vitamin C in adults with sepsis in the intensive care unit. N Engl J Med. 2022; 386:2387–2398
    1. Angriman F, Muttalib F, Lamontagne F, et al.; LOVIT Investigators: IV vitamin C in adults with sepsis: A Bayesian reanalysis of a randomized controlled trial*. Crit Care Med. 2023; 51:e152–e156
    1. Hammond NE, Zampieri FG, Tanna GL, et al.: Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis. NEJM Evid. 2022; 1(2)
    1. Reintam Blaser A, Alhazzani W, Belley-Cote E, et al.: Intravenous vitamin C therapy in adult patients with sepsis: A rapid practice guideline. Acta Anaesthesiol Scand. 2023 Jul 27. [online ahead of print]

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