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. 2024 Apr;66(4):582-589.
doi: 10.1016/j.amepre.2023.11.009. Epub 2023 Nov 14.

Trends in Cardiovascular Disease Mortality Rates and Excess Deaths, 2010-2022

Rebecca C Woodruff  1 , Xin Tong  2 , Sadiya S Khan  3 , Nilay S Shah  3 , Sandra L Jackson  2 , Fleetwood Loustalot  2 , Adam S Vaughan  2
Affiliations

Trends in Cardiovascular Disease Mortality Rates and Excess Deaths, 2010-2022

Rebecca C Woodruff et al. Am J Prev Med. 2024 Apr.

Abstract

Introduction: Cardiovascular disease (CVD) mortality increased during the initial years of the COVID-19 pandemic, but whether these trends endured in 2022 is unknown. This analysis describes temporal trends in CVD death rates from 2010 to 2022 and estimates excess CVD deaths from 2020 to 2022.

Methods: Using national mortality data from the National Vital Statistics System, deaths among adults aged ≥35 years were classified by underlying cause of death International Classification of Diseases 10th Revision codes for CVD (I00-I99), heart disease (I00-I09, I11, I13, I20-I51), and stroke (I60-I69). Analyses in Joinpoint software identified trends in CVD age-adjusted mortality rates (AAMR) per 100,000 and estimated the number of excess CVD deaths from 2020 to 2022.

Results: During 2010-2022, 10,951,403 CVD deaths occurred (75.6% heart disease, 16.9% stroke). The national CVD AAMR declined by 8.9% from 2010 to 2019 (456.6-416.0 per 100,000) and then increased by 9.3% from 2019 to 2022 to 454.5 per 100,000, which approximated the 2010 rate (456.7 per 100,000). From 2020 to 2022, 228,524 excess CVD deaths occurred, which was 9% more CVD deaths than expected based on trends from 2010 to 2019. Results varied by CVD subtype and population subgroup.

Conclusions: Despite stabilization of the public health emergency, declines in CVD mortality rates reversed in 2020 and remained high in 2022, representing almost a decade of lost progress and over 228,000 excess CVD deaths. Findings underscore the importance of prioritizing prevention and management of CVD to improve outcomes.

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Figures

Figure 1.
Figure 1.. Age-Adjusted Mortality Rates of Cardiovascular Disease, Heart Disease, and Stroke Among Adults Aged ≥35 Years—United States, 2010-2022
Figure displays annual trends from 2010 to 2022 in age-adjusted mortality rate (AAMR) for deaths with International Classification of Diseases, 10th Revision, Clinical Modification codes for A. cardiovascular disease (CVD, I00-I99) or heart disease (I00-I09, I11, I13, I20-I51) or B. stroke (I60-I69) listed as the underlying cause of death. The dashed line connects the 2022 AAMR with the most recent year in which the 95% CIs overlap.
See this image and copyright information in PMC

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