Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 16;21(1):818.
doi: 10.1186/s12967-023-04690-7.

The impact of fibrotic diseases on global mortality from 1990 to 2019

Affiliations

The impact of fibrotic diseases on global mortality from 1990 to 2019

Henricus A M Mutsaers et al. J Transl Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Impact of Fibrotic Diseases on Global Mortality from 1990 to 2019. A Selected causes of death and their ranking in 1990 and 2019, based on their percentage contribution to global deaths. B Trend of percentage of global deaths attributable to fibrotic diseases from 1990 to 2019

References

    1. Rockey DC, Bell PD, Hill JA. Fibrosis—a common pathway to organ injury and failure. N Engl J Med. 2015;372(12):1138–1149. doi: 10.1056/NEJMra1300575. - DOI - PubMed
    1. Diseases GBD, Injuries C. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204–1222. doi: 10.1016/S0140-6736(20)30925-9. - DOI - PMC - PubMed
    1. Yamauchi M, Barker TH, Gibbons DL, Kurie JM. The fibrotic tumor stroma. J Clin Invest. 2018;128(1):16–25. doi: 10.1172/JCI93554. - DOI - PMC - PubMed
    1. Piersma B, Hayward MK, Weaver VM. Fibrosis and cancer: a strained relationship. Biochim Biophys Acta Rev Cancer. 2020;1873(2):188356. doi: 10.1016/j.bbcan.2020.188356. - DOI - PMC - PubMed
    1. Boulter L, Bullock E, Mabruk Z, Brunton VG. The fibrotic and immune microenvironments as targetable drivers of metastasis. Br J Cancer. 2021;124(1):27–36. doi: 10.1038/s41416-020-01172-1. - DOI - PMC - PubMed

Publication types

LinkOut - more resources