Solitary Extramedullary Plasmacytoma of Nasal Cavity

Abstract

Solitary extramedullary plasmacytoma (SEP) of the nasal cavity is a rare neoplastic condition characterized by the localized proliferation of abnormal plasma cells. We present a case of SEP involving the nasal cavity in a 40-year-old male patient who presented with nasal obstruction and recurrent epistaxis. The diagnosis was confirmed through clinical evaluation, imaging studies, and histopathological examination of excised specimen. The patient underwent trans-nasal endoscopic excision of nasal mass without any adjuvant therapy, which resulted in successful local control. This case report highlights the clinical presentation, diagnostic approach, treatment modalities, and favourable prognosis associated with solitary extramedullary plasmacytoma of the nasal cavity.

Keywords: Angiofibroma; Epistaxis; Multiple myeloma; Nasal mass; Plasmacytoma.

Fig. 1

Endoscopic image of left nasal cavity showing vascular mass (black asterix)

Fig. 2

Contrast enhanced CT showing hyperintense mass in left nasal nasal cavity (denoted with red arrow)

Fig. 3

Image showing excised nasal mass

Fig. 4

Histopathological section showing mucosa and sub epithelium with proliferation of plasma cells with round to oval eccentric nuclei and eosinophilic cytoplasm. (H&E; 40X). (black arrow)