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. 2024 Feb 16;13(2):247-253.
doi: 10.1093/ehjacc/zuad138.

Beta-blocker and calcium-channel blocker toxicity: current evidence on evaluation and management

Affiliations

Beta-blocker and calcium-channel blocker toxicity: current evidence on evaluation and management

Charlotte E Goldfine et al. Eur Heart J Acute Cardiovasc Care. .

Abstract

Beta-blocker and calcium-channel blocker overdoses are associated with severe morbidity and mortality; therefore, it is important to recognize and appropriately treat individuals with toxicity. The most common clinical findings in toxicity are bradycardia and hypotension. In addition to supportive care and cardiac monitoring, specific treatment includes administration of calcium salts, vasopressors, and high-dose insulin euglycaemia treatment. Other advanced treatments (e.g. ECMO) may be indicated depending on the severity of toxicity and specific agents involved.

Keywords: Beta-blocker; Calcium-channel blocker; Cardiovascular drug toxicity; Overdose; Toxicity.

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Conflict of interest statement

Conflict of interest: None declared.

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