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. 2024 Nov;39(8):1708-1714.
doi: 10.1177/02676591231216794. Epub 2023 Nov 17.

Influence of minimal invasive extracorporeal circuits on dialysis dependent patients undergoing cardiac surgery

Thai Duy Nguyen  1 , Mohammed Morjan  2 , Khaldoun Ali  3 , Ingo Breitenbach  3 , Wolfgang Harringer  3 , Aschraf El-Essawi  4
Affiliations

Influence of minimal invasive extracorporeal circuits on dialysis dependent patients undergoing cardiac surgery

Thai Duy Nguyen et al. Perfusion. 2024 Nov.

Abstract

Introduction: Cardiac surgery in patients on chronic renal dialysis is associated with significant morbidity and mortality. Minimally invasive extracorporeal circuits (MiECC) have shown a positive impact on patient outcome in different high-risk populations. This retrospective study compares the outcome of these high-risk patients undergoing heart surgery either with a MiECC or a conventional extracorporeal circulation (CECC).

Methods: This is a single-center experience including 131 consecutive dialysis dependent patients undergoing cardiac surgery between January 2006 and December 2016. A propensity score matching was employed leaving 30 matched cases in each group.

Results: After propensity score matching the 30-day mortality was significantly lower in the MiECC group (n = 3 (10%) vs n = 10 (33%) in the CECC group, p = .028). Further, intraoperative transfused units of packed red blood cells were lower in the MiECC group (1.4 ± 1.8 units vs 2.8 ± 1.7, p < .001).

Conclusions: There are evident advantages to using MiECC in dialysis dependent patients, especially regarding mortality. These findings necessitate additional research in MiECC usage in high-risk populations.

Keywords: MiECC; cardiac surgery; cardiopulmonary bypass; dialysis; end stage renal disease; extracorporeal circulation; minimal invasive.

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Conflict of interest statement

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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