Comment
doi: 10.1016/j.kint.2023.09.019.
The aberrant glycolysis in kidney proximal tubule: potential therapeutic target for DKD
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- PMID: 37981426
- DOI: 10.1016/j.kint.2023.09.019
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Comment
The aberrant glycolysis in kidney proximal tubule: potential therapeutic target for DKD
Kidney Int.
2023 Dec.
Abstract
The presence of glycolysis in kidney proximal tubule has been long debated. However, recent reports suggest that aberrant glycolysis is induced in pathologic conditions and may play a critical role in kidney damage. Azushima et al. provided additional evidence that the accumulation of glycolysis-derived lactate could be the clue to understanding the pathogenesis of diabetic kidney disease.
Copyright © 2023 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
Comment on
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Abnormal lactate metabolism is linked to albuminuria and kidney injury in diabetic nephropathy.Kidney Int. 2023 Dec;104(6):1135-1149. doi: 10.1016/j.kint.2023.08.006. Epub 2023 Oct 16. Kidney Int. 2023. PMID: 37843477
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