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Clinical Trial
. 1986 Dec 20;70(13):801-2.

Blood oxygen saturation levels during conscious sedation with midazolam. A report of 16 cases

J A Roelofse, P van der Bijl, J J Joubert, H S Breytenbach
  • PMID: 3798264
Clinical Trial

Blood oxygen saturation levels during conscious sedation with midazolam. A report of 16 cases

J A Roelofse et al. S Afr Med J. .

Abstract

In a double-blind randomized study on 16 healthy individuals, two groups of subjects (8 in each group) received either midazolam (Dormicum; Roche) 0.1 mg/kg or placebo intravenously for conscious sedation during oral surgical procedures. Oxygen saturation of the blood was measured at different stages. Ten minutes after administration of the drug, the percentage oxygen saturation was significantly lower (P less than 0.05) in the midazolam group than in the placebo group.

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