Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;25(12):1831-1838.
doi: 10.1007/s11886-023-01996-2. Epub 2023 Nov 20.

Global Cardiovascular Research: Gaps and Opportunities

Affiliations
Review

Global Cardiovascular Research: Gaps and Opportunities

Maha Inam et al. Curr Cardiol Rep. 2023 Dec.

Abstract

Purpose of review: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. CVDs contribute to a large health and economic burden on a global scale. We aim to describe the current landscape of global cardiovascular research, highlight significant findings, and identify potential opportunities for further studies.

Recent findings: There has been remarkable research output regarding cardiovascular health in recent decades. Large-scale collaborative studies have made impactful strides in identifying modifiable risk factors and forming evidence-based guidelines to facilitate improved cardiovascular care and outcomes. However, there are significant CVD disparities between high- and low- income countries which require interventions to mitigate these inequalities. Encouraging collaborative partnerships, strengthening research capacity in low-resource settings, and promoting equity in research are fundamental strategic approaches to help improve global cardiovascular research.

Keywords: Cardiovascular disease burden; Cardiovascular research; Global cardiovascular health; Healthcare disparities.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest The other authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Global CVD statistics and factors affecting global cardiovascular research

References

    1. Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016;388(10053):1459–544. - PMC - PubMed
    1. Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019. J Am Coll Cardiol. 2020;76(25):2982–3021.

      •• This study forms the prime resource which outlines the global magnitude of total CVD burden (incidence, prevalence, case fatality, mortality, health risks), identifies underlying causes of CVD death, and links them to relevant risk factors.

    1. The top 10 causes of death [Internet]. World Health Organization; 2020. Dec 9 [cited 2023 Sep 1]. Available from: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.
    1. Murray CJL, Lopez AD. Measuring the global burden of disease. N Engl J Med. 2013;369(5):448–57. - PubMed
    1. Birger M, Kaldjian AS, Roth GA, Moran AE, Dieleman JL, Bellows BK. Spending on cardiovascular disease and cardiovascular risk factors in the United States: 1996 to 2016. Circulation. 2021;144(4):271–82. - PMC - PubMed

Publication types

LinkOut - more resources