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. 2024 Jan:168:107689.
doi: 10.1016/j.compbiomed.2023.107689. Epub 2023 Nov 8.

Human body numerical simulation: An accurate model for a thigh subjected to a cold treatment

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Human body numerical simulation: An accurate model for a thigh subjected to a cold treatment

P Michaux et al. Comput Biol Med. 2024 Jan.

Abstract

This article presents the development of a digital twin model of a thigh portion subjected to various thermal treatments. Two scenarios are investigated: cold water immersion (CWI) and whole body cryotherapy (WBC), for which the comparison of numerical results with experimental measurements validates the consistency of the developed model. The use of real geometry on a first subject demonstrates the high heterogeneity of the temperature field and the need for accurate geometry. A second subject with thicker adipose tissue highlights the impact of the subject's actual morphology on the validity of the treatment and the necessity to work with real geometry in order to optimize cold modalities and develop personalized treatments.

Keywords: Bioheat equation; Cryotherapy; Finite element model; Thermal stress; Water immersion.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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