ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis

Matthew J Page¹, Jonathan A C Sterne^{2

3

4}, Isabelle Boutron⁵, Asbjørn Hróbjartsson^{6

7}, Jamie J Kirkham⁸, Tianjing Li⁹, Andreas Lundh^{6

7

10}, Evan Mayo-Wilson¹¹, Joanne E McKenzie¹, Lesley A Stewart¹², Alex J Sutton¹³, Lisa Bero¹⁴, Adam G Dunn¹⁵, Kerry Dwan¹⁶, Roy G Elbers¹⁷, Raju Kanukula¹, Joerg J Meerpohl^{18

19}, Erick H Turner^{20

21}, Julian P T Higgins^{2

3}

Affiliations

¹ Methods in Evidence Synthesis Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
² Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
³ National Institute for Health and Care Research Bristol Biomedical Research Centre, Bristol, UK.
⁴ Health Data Research UK South-West, Bristol, UK.
⁵ Université de Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Paris, France.
⁶ Centre for Evidence-Based Medicine Odense and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
⁷ Open Patient data Exploratory Network, Odense University Hospital, Odense, Denmark.
⁸ Centre for Biostatistics, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
⁹ Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
¹⁰ Department of Respiratory Medicine and Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
¹¹ Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
¹² Centre for Reviews and Dissemination, University of York, York, UK.
¹³ Department of Population Health Sciences, University of Leicester, Leicester, UK.
¹⁴ Center for Bioethics and Humanities, University of Colorado, Aurora, CO, USA.
¹⁵ Biomedical Informatics and Digital Health, School of Medical Sciences, University of Sydney, Sydney, NSW, Australia.
¹⁶ Liverpool School of Tropical Medicine, Liverpool, UK.
¹⁷ Department of General Practice, Intellectual Disability Medicine, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands.
¹⁸ Institute for Evidence in Medicine, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
¹⁹ Cochrane Germany, Cochrane Germany Foundation, Freiburg, Germany.
²⁰ Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA.
²¹ Behavioral Health and Neurosciences Division, Veterans Affairs Portland Health Care System, Portland, OR, USA.

PMID: 37984978
DOI: 10.1136/bmj-2023-076754

Meta-Analysis

ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis

Matthew J Page et al. BMJ. 2023.

. 2023 Nov 20:383:e076754.

doi: 10.1136/bmj-2023-076754.

Authors

Affiliations

¹ Methods in Evidence Synthesis Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
² Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
³ National Institute for Health and Care Research Bristol Biomedical Research Centre, Bristol, UK.
⁴ Health Data Research UK South-West, Bristol, UK.
⁵ Université de Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Paris, France.
⁶ Centre for Evidence-Based Medicine Odense and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
⁷ Open Patient data Exploratory Network, Odense University Hospital, Odense, Denmark.
⁸ Centre for Biostatistics, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
⁹ Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
¹⁰ Department of Respiratory Medicine and Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.
¹¹ Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
¹² Centre for Reviews and Dissemination, University of York, York, UK.
¹³ Department of Population Health Sciences, University of Leicester, Leicester, UK.
¹⁴ Center for Bioethics and Humanities, University of Colorado, Aurora, CO, USA.
¹⁵ Biomedical Informatics and Digital Health, School of Medical Sciences, University of Sydney, Sydney, NSW, Australia.
¹⁶ Liverpool School of Tropical Medicine, Liverpool, UK.
¹⁷ Department of General Practice, Intellectual Disability Medicine, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands.
¹⁸ Institute for Evidence in Medicine, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
¹⁹ Cochrane Germany, Cochrane Germany Foundation, Freiburg, Germany.
²⁰ Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA.
²¹ Behavioral Health and Neurosciences Division, Veterans Affairs Portland Health Care System, Portland, OR, USA.

PMID: 37984978
DOI: 10.1136/bmj-2023-076754

No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: All authors have completed the ICMJE disclosure form at https://www.icmje.org/disclosure-of-interest/ and declare: no support from any organisation for the submitted work; JJK is a statistical editor for The BMJ, for which he receives remuneration; EM-W has received grants/contracts from the Patient Centered Outcomes Research Institute, National Institutes of Health, Arnold Ventures, and Robert Wood Johnson Foundation, has received consulting fees for editorial work from Origin Editorial, payment/honorariums from the American Public Health Association and National Institutes of Health, and has an unpaid leadership role in the American Psychological Association; LB has received grants/contracts from the state of Colorado, Cochrane, and the US Environmental Protection Agency, has received consulting fees for work as a conflict of interest advisor from Health Canada, has received support for travel from the National Academy of Science Engineering and Medicine, Cochrane and the World Congress on Research Integrity, and has an unpaid chair role for the National Academy of Science Engineering and Medicine committees; EHT has received an honorarium for a lecture on publication bias from the University of British Columbia, Canada; all other authors declare having no competing interests.

Comment in

Will the ROB-ME checklist prevent omission bias in meta-analyses?
Freemantle N, Irs A. Freemantle N, et al. BMJ. 2023 Nov 20;383:2653. doi: 10.1136/bmj.p2653. BMJ. 2023. PMID: 37984969 No abstract available.

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Grants and funding

MR/J004855/1/MRC_/Medical Research Council/United Kingdom

LinkOut - more resources

Full Text Sources
- HighWire
- Ovid Technologies, Inc.

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis

Affiliations

ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis

Authors

Affiliations

Conflict of interest statement

Comment in

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources