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Comment
. 2023 Nov 21;4(11):101291.
doi: 10.1016/j.xcrm.2023.101291.

Immune imprinting as a barrier to effective COVID-19 vaccines

Julia N Faraone  1 , Shan-Lu Liu  2
Affiliations
Comment

Immune imprinting as a barrier to effective COVID-19 vaccines

Julia N Faraone et al. Cell Rep Med. .

Abstract

Wang and colleagues show that immune imprinting impairs neutralizing antibody titers for bivalent mRNA vaccination against SARS-CoV-2 Omicron subvariants. Imprinting from three doses of monovalent vaccine can be alleviated by BA.5 or BQ-lineage breakthrough infection but not by a bivalent booster.1.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

References

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