doi: 10.1016/j.cell.2023.10.027.
Staphylococcus scratches its itch
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- PMID: 37995654
- DOI: 10.1016/j.cell.2023.10.027
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Staphylococcus scratches its itch
Cell.
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Abstract
Itch exacerbates infection and inflammation-associated skin pathology. In this issue of Cell, Deng et al. identify a V8 protease released by Staphylococcus aureus triggering itch via neuronal protease-activated receptor 1. In so doing, they uncover profound consequences of microbial neurosensory modulation and the ensuing scratch-induced tissue damage that potentiates infection.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests S.N. is on the SAB of Seed Inc. and receives funding from Takeda Pharmaceuticals.
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