Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

doi:10.1016/S1473-3099(23)00690-4

. 2024 Jan;24(1):e1-e3.

doi: 10.1016/S1473-3099(23)00690-4. Epub 2023 Nov 20.

Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

Metodi V Stankov¹, Markus Hoffmann², Rodrigo Gutierrez Jauregui³, Anne Cossmann¹, Gema Morillas Ramos¹, Theresa Graalmann⁴, Emily Jo Winter⁵, Michaela Friedrichsen³, Inga Ravens³, Tamara Ilievska³, Jasmin Ristenpart³, Anja Schimrock³, Stefanie Willenzon³, Gerrit Ahrenstorf¹, Torsten Witte⁶, Reinhold Förster⁷, Amy Kempf², Stefan Pöhlmann², Swantje I Hammerschmidt³, Alexandra Dopfer-Jablonka⁸, Georg M N Behrens⁹

Affiliations

¹ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.
² Infection Biology Unit, German Primate Centre, Göttingen, Germany; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany.
³ Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany.
⁴ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; Junior Research Group for Translational Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.
⁵ Junior Research Group for Translational Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.
⁶ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; Cluster of Excellence RESIST, Hannover Medical School, 30625 Hannover, Germany.
⁷ Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany; Cluster of Excellence RESIST, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.
⁸ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.
⁹ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany; CiiM, Centre for Individualized Infection Medicine, Hannover, Germany. Electronic address: behrens.georg@mh-hannover.de.

PMID: 37995739
DOI: 10.1016/S1473-3099(23)00690-4

Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

Metodi V Stankov et al. Lancet Infect Dis. 2024 Jan.

. 2024 Jan;24(1):e1-e3.

doi: 10.1016/S1473-3099(23)00690-4. Epub 2023 Nov 20.

Authors

Affiliations

¹ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.
² Infection Biology Unit, German Primate Centre, Göttingen, Germany; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany.
³ Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany.
⁴ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; Junior Research Group for Translational Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.
⁵ Junior Research Group for Translational Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.
⁶ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; Cluster of Excellence RESIST, Hannover Medical School, 30625 Hannover, Germany.
⁷ Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany; Cluster of Excellence RESIST, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.
⁸ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.
⁹ Department of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany; CiiM, Centre for Individualized Infection Medicine, Hannover, Germany. Electronic address: behrens.georg@mh-hannover.de.

PMID: 37995739
DOI: 10.1016/S1473-3099(23)00690-4

No abstract available

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Conflict of interest statement

MH, AK, and SP did the contract research (testing of vaccinee sera for neutralising activity against SARS-CoV-2) for Valneva, unrelated to this work. GMNB served as an adviser for Moderna, unrelated to this work. SP served as an adviser for BioNTech, unrelated to this work. AD-J and TW served as an adviser for Pfizer, unrelated to this work. All other authors declare no competing interests. MVS, MH, and RGJ are co-first authors. AD-J and GMNB are co-senior authors.

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Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

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Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

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