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Review
. 2023 Nov;36 Suppl 1(Suppl 1):59-63.
doi: 10.37201/req/s01.14.2023. Epub 2023 Nov 24.

New trends in antifungal treatment: What is coming up?

J Guinea  1
Affiliations
Review

New trends in antifungal treatment: What is coming up?

J Guinea. Rev Esp Quimioter. 2023 Nov.

Abstract

New antifungal agents are needed to overcome limitations of available ones such as poor pharmacokinetic traits, toxicity, drug-drug interactions, limited clinical efficacy, and emerging antifungal resistance. New antifungal drugs belong to well-known families (azoles, polyenes, or beta-d-glucan synthase inhibitors) or to drug families showing completely new mechanisms of action. Some drugs have a head start in terms of potential to reach the clinical setting and are here reviewed.

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Figures

Figure 1
Figure 1
Graph showing interactions among the three elements playing a role in invasive fungal infections (patients, aetiological agents, and antifungal drugs)
Figure 2
Figure 2
New antifungal agents in the horizon for the treatment of fungal infections
See this image and copyright information in PMC

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