From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt-The Biological Roller Coaster to Which the Renin-Angiotensin System Has Had to Adapt: An Editorial

György L Nádasy¹, András Balla^{1

2}, Mária Szekeres^{1

3}

Affiliations

¹ Department of Physiology, Faculty of Medicine, Semmelweis University, 37-47 Tűzoltó Street, 1094 Budapest, Hungary.
² Laboratory of Molecular Physiology, Eötvös Loránd Research Network, Research Centre for Natural Sciences, 2 Magyar Tudósok Körútja, 1117 Budapest, Hungary.
³ Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, 17 Vas Street, 1088 Budapest, Hungary.

PMID: 38002004
PMCID: PMC10669630
DOI: 10.3390/biomedicines11113004

Editorial

From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt-The Biological Roller Coaster to Which the Renin-Angiotensin System Has Had to Adapt: An Editorial

György L Nádasy et al. Biomedicines. 2023.

. 2023 Nov 9;11(11):3004.

doi: 10.3390/biomedicines11113004.

Authors

György L Nádasy¹, András Balla^{1

2}, Mária Szekeres^{1

3}

Affiliations

¹ Department of Physiology, Faculty of Medicine, Semmelweis University, 37-47 Tűzoltó Street, 1094 Budapest, Hungary.
² Laboratory of Molecular Physiology, Eötvös Loránd Research Network, Research Centre for Natural Sciences, 2 Magyar Tudósok Körútja, 1117 Budapest, Hungary.
³ Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, 17 Vas Street, 1088 Budapest, Hungary.

PMID: 38002004
PMCID: PMC10669630
DOI: 10.3390/biomedicines11113004

Abstract

Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs) [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

1. Hunyady L., Catt K.J. Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. (Review) Mol. Endocrinol. 2006;20:953–970. doi: 10.1210/me.2004-0536. - DOI - PubMed
1. Toth A., Turu G., Hunyady L., Balla A. Novel mechanisms of G-protein.coupled receptors functions: QT1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk. Best Pract. Red Clin. Endocrynol. Metabol. 2018;32:69–82. doi: 10.1016/j.beem.2018.02.003. - DOI - PubMed
1. Gem J.B., Kovacs K.B., Szalai L., Szakadati G., Porkolab E., Szalai B., Turu G., Toth A.D., Szekeres M., Hunyady L., et al. Characterization of Type 1 Angiotensin receptor activation induced dual-specificity MAPK phosphatase gene expression changes in rat vascular smooth muscle cells. Cells. 2021;10:3538. doi: 10.3390/cells10123538. - DOI - PMC - PubMed
1. Ungvari Z., Tarantini S., Donato A.J., Galvan V., Csiszar A. Mechanism of vascular aging. Circ. Res. 2018;123:849–867. doi: 10.1161/CIRCRESAHA.118.311378. - DOI - PMC - PubMed
1. Iovino M., Guastamacchia E., Giagulli V.A., Licchelli B., Triggiani V. Vasopressin secretion control: Central neural path-ways, neurotransmitters and effects of drugs. Curr. Pharm. Design. 2012;18:4714–4724. doi: 10.2174/138161212802651607. - DOI - PubMed

Publication types

Actions

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt-The Biological Roller Coaster to Which the Renin-Angiotensin System Has Had to Adapt: An Editorial

Affiliations

From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt-The Biological Roller Coaster to Which the Renin-Angiotensin System Has Had to Adapt: An Editorial

Authors

Affiliations

Abstract

Conflict of interest statement

References

Publication types