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Review
. 2023 Nov 11;11(11):3031.
doi: 10.3390/biomedicines11113031.

The Evolvement of OCT and OCT-A in Identifying Multiple Sclerosis Biomarkers

Vlad Constantin Donica  1 , Anisia Iuliana Alexa  1 , Irina Andreea Pavel  1 , Ciprian Danielescu  1 , Manuela Andreea Ciapă  2 , Alexandra Lori Donica  3 , Camelia Margareta Bogdănici  1
Affiliations
Review

The Evolvement of OCT and OCT-A in Identifying Multiple Sclerosis Biomarkers

Vlad Constantin Donica et al. Biomedicines. .

Abstract

The prevalence of multiple sclerosis (MS) has been increasing among young people in developing countries over the last years. With the continuous development of new technology, the diagnosis and follow-up of these patients has received new parameters that physicians may use in their practice. This paper reviews the main biomarkers identified through Optical Coherence Tomography Angiography (OCT-A) involved in the development and progression of MS and investigates the role it may have in detecting changes to the central nervous system (CNS).

Keywords: OCT; OCT-A; demyelinating disease; multiple sclerosis; optical coherence tomography; optical coherence tomography angiography; retinal vascular density.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Retinal structural layers [7,8].
Figure 2
Figure 2
A schematic representation of the current study design.
See this image and copyright information in PMC

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