Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Oct 24;10(11):1721.
doi: 10.3390/children10111721.

Concerns Related to the Consequences of Pediatric Cannabis Use: A 360-Degree View

Affiliations
Review

Concerns Related to the Consequences of Pediatric Cannabis Use: A 360-Degree View

Flavia Padoan et al. Children (Basel). .

Abstract

Cannabis, a plant known for its recreational use, has gained global attention due to its widespread use and addiction potential. Derived from the Cannabis sativa plant, it contains a rich array of phytochemicals concentrated in resin-rich trichomes. The main cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), interact with CB1 and CB2 receptors, influencing various physiological processes. Particularly concerning is its prevalence among adolescents, often driven by the need for social connection and anxiety alleviation. This paper provides a comprehensive overview of cannabis use, its effects, and potential health risks, especially in adolescent consumption. It covers short-term and long-term effects on different body systems and mental health and highlights the need for informed decision making and public health initiatives, particularly regarding adolescent cannabis use.

Keywords: adolescent cannabis use; cannabis; cannabis short-term and long-term effects; medical uses of cannabis; public health initiatives.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Large M., Sharma S., Compton M.T., Slade T., Nielssen O. Cannabis use and earlier onset of psychosis: A systematic meta-analysi. Arch. Gen. Psychiatry. 2011;68:555–561. doi: 10.1001/archgenpsychiatry.2011.5. - DOI - PubMed
    1. Larramendi C.H., López-Matas M., Ferrer A., Huertas J., Pagán J.A., Navarro L., García-Abujeta J.L., Andreu C., Carnés J. Prevalence of sensitization to Cannabis sativa. Lipid-transfer and thaumatin-like proteins are relevant allergens. Int. Arch. Allergy Immunol. 2013;162:115–122. doi: 10.1159/000351068. - DOI - PubMed
    1. Farinon B., Molinari R., Costantini L., Merendino N. The seed of industrial hemp (Cannabis sativa L.): Nutritional Quality and Potential Functionality for Human Health and Nutrition. Nutrients. 2020;12:1935. doi: 10.3390/nu12071935. - DOI - PMC - PubMed
    1. Happyana N., Agnolet S., Muntendam R., Van Dam A., Schneider B., Kayser O. Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. Phytochemistry. 2012;87:51–59. doi: 10.1016/j.phytochem.2012.11.001. - DOI - PubMed
    1. Kitdumrongthum S., Trachootham D. An Individuality of Response to Cannabinoids: Challenges in Safety and Efficacy of Cannabis Products. Molecules. 2023;28:2791. doi: 10.3390/molecules28062791. - DOI - PMC - PubMed

LinkOut - more resources