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Review
. 2023 Nov 14;24(22):16323.
doi: 10.3390/ijms242216323.

Phytochemistry and Biological Studies of Endemic Hawaiian Plants

Pornphimon Meesakul  1 , Tyler Shea  2 , Roland Fenstemacher  3 , Shi Xuan Wong  4 , Yutaka Kuroki  4 , Aya Wada  4 , Shugeng Cao  1
Affiliations
Review

Phytochemistry and Biological Studies of Endemic Hawaiian Plants

Pornphimon Meesakul et al. Int J Mol Sci. .

Abstract

The Hawaiian Islands are renowned for their exceptional biodiversity and are host to a plethora of endemic plant species, which have been utilized in traditional Hawaiian medicine. This scientific review provides an in-depth analysis of the phytochemistry and biological studies of selected endemic Hawaiian plants, highlighting their medicinal properties and therapeutic potential. A literature search was conducted, utilizing major academic databases such as SciFinder, Scopus, Web of Science, PubMed, Google Scholar, Science Direct, and the Scientific Information Database. The primary objective of this search was to identify relevant scholarly articles pertaining to the topic of the review, which focused on the phytochemistry and biological studies of endemic Hawaiian plants. Utilizing these databases, a comprehensive range of literature was obtained, facilitating a comprehensive examination of the subject matter. This review emphasizes the rich phytochemical diversity and biological activities found in Endemic Hawaiian plants, showcasing their potential as sources of novel therapeutic agents. Given the unique biodiversity of Hawaii and the cultural significance of these plants, continued scientific exploration, conservation, and sustainable utilization of these valuable resources is necessary to unlock the full potential of these plant species in drug discovery and natural product-based therapeutics.

Keywords: Hawaiian plants; biological activities; biological studies; chemical constituents; endemic Hawaiian plant; phytochemistry.

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Conflict of interest statement

Authors Shi Xuan Wong, Aya Wada, and Yutaka Kuroki were employed by the company Delightex Pte. Ltd., Singapore. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Alkaloids from A. glauca var. glauca.
Figure 2
Figure 2
Polyacetylenes from Hawaiian Bidens species.
Figure 3
Figure 3
Flavonoids from Hawaiian Bidens species.
Figure 4
Figure 4
Alkaloid from C. obovata.
Figure 5
Figure 5
Flavonoids glucoside from C. persicifolia.
Figure 6
Figure 6
Iridoid glycosides from C. ernodeoides.
Figure 7
Figure 7
Flavonoids from D. arborea.
Figure 8
Figure 8
Alkaloids from E. sandwicensis.
Figure 9
Figure 9
Flavonoids from E. sandwicensis.
Figure 10
Figure 10
Flavonoid glucoside from H. arborescens.
Figure 11
Figure 11
Flavonoid glucoside from H. sandwicensis.
Figure 12
Figure 12
Alkaloid from L. yuccoides.
Figure 13
Figure 13
Flavonoids from Hawaiian Lysimachia genus.
Figure 14
Figure 14
Acetophenones and 2H-benzopyranes from M. barbigera.
Figure 15
Figure 15
Alkaloids and furoquinolines from P. campanulatum.
Figure 16
Figure 16
Alkaloids from R. sandwicensis.
Figure 17
Figure 17
Alkaloids and flavonoids from S. chrysophylla.
Figure 18
Figure 18
Flavonoid and cinnamate ester from V. calycinum and V. reticulatum.
Figure 19
Figure 19
Daphnane diterpenes from W. monticola.
Figure 20
Figure 20
Lignans and coumarin from W. uva-ursi.
Figure 21
Figure 21
Alkaloids, pyranocoumarins, triterpenes, and flavonoid from Z. dipetalum.
See this image and copyright information in PMC

References

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