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. 2023 Oct 25;12(11):1278.
doi: 10.3390/pathogens12111278.

Genetic Evaluation of Bovine Papillomavirus Types Associated with Teat Papillomatosis in Polish Dairy Cattle with the Report of a New Putative Type

Paulina Pyrek  1   2 , Michał Bednarski  3 , Jarosław Popiel  1 , Magdalena Siedlecka  3 , Magdalena Karwańska  3
Affiliations

Genetic Evaluation of Bovine Papillomavirus Types Associated with Teat Papillomatosis in Polish Dairy Cattle with the Report of a New Putative Type

Paulina Pyrek et al. Pathogens. .

Abstract

Teat papillomatosis is reported to be one of the factors causing mastitis and milk losses in dairy cattle. Little is known about bovine papillomavirus (BPV) circulation in the European cattle population, and no reports can yet be found about its prevalence in Polish herds. In this study, 177 BPV-like lesions were collected from teats of 109 slaughtered cows. BPV was identified in 39 of the examined animals, using PCR amplification and Sanger dideoxy sequencing. In total, 10 BPV types were isolated, among which the most common were infections caused by types 8 and 7. Macroscopically, "rice-grain" type lesions dominated (76%) and were mainly found on one teat (57.4%). The diversity of BPV types causing teat papillomatosis in Polish cows seems to be large, with nine already known types isolated and a new putative type found. The spread of new types among the worldwide cattle population can be seen for the first time, as type 25 and so called isolates BPV42 and BPV43 were found in the European cattle population.

Keywords: Poland; bovine papillomavirus; cattle; papillomatosis; teat.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Skin papillomas’ macroscopic view, found in examined population of Polish cows. (A)—“rice-grain” shape consisting of a white elongated protuberance, (B)—Cauliflower-like skin papilloma, (C)—Filamentous skin papilloma, (D)—Pedunculated skin papilloma.
Figure 2
Figure 2
Average number of lesions per teat depending on the macroscopic feature and BPV type isolated from the lesions.
Figure 3
Figure 3
Box-and-whisker plot showing the number of lesions found on one teat depending on the BPV type isolated.
Figure 4
Figure 4
Number of animals affected by isolated BPV types.
Figure 5
Figure 5
Phylogenetic analysis based on the partial major capsid protein L1 gene sequences of BPV isolates from Polish cattle. Phylogenetic tree was generated by the maximum-likelihood method with 1000 bootstrap replicates through the MEGA v11.0 software.
See this image and copyright information in PMC

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