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. 2023 Oct 30;15(11):2176.
doi: 10.3390/v15112176.

Epidemiology of Influenza-like Illness and Respiratory Viral Etiology in Adult Patients in Taiyuan City, Shanxi Province, China between 2018 and 2019

Zhao Jia  1   2 , Puna Xue  1   2 , Ruihong Gao  1   2 , Rui Wang  2 , Lifeng Zhao  2 , Zhihong Zuo  2 , Li Gao  2 , Rui Han  2 , Hong Yao  1 , Jiane Guo  1   2 , Jihong Xu  2 , Zhen Zhu  3 , Jitao Wang  1   2
Affiliations

Epidemiology of Influenza-like Illness and Respiratory Viral Etiology in Adult Patients in Taiyuan City, Shanxi Province, China between 2018 and 2019

Zhao Jia et al. Viruses. .

Abstract

To determine the epidemiological status of influenza and understand the distribution of common respiratory viruses in adult patients with influenza-like illness (ILI) cases in Taiyuan City, Shanxi Province, China, epidemiological data between 2018 and 2019 were retrieved from the China Influenza Surveillance Information System, and two sentinel ILI surveillance hospitals were selected for sample collection. All specimens were screened for influenza virus (IFV) and the other 14 common respiratory viruses using real-time polymerase chain reaction. The results of the 2-year ILI surveillance showed that 26,205 (1.37%) of the 1,907,869 outpatients and emergency patients presented with ILI, with an average annual incidence of 297.75 per 100,000 individuals, and ILI cases were predominant in children <15 years (21,348 patients, 81.47%). Of the 2713 specimens collected from adult patients with ILI, the overall detection rate of respiratory viruses was 20.13%, with IFV being the most frequently detected (11.79%) and at a relatively lower rate than other respiratory viruses. Further subtype analysis indicated an alternating or mixed prevalence of H1N1 (2009), H3N2, Victoria, and Yamagata subtypes. This study provides a baseline epidemiological characterization of ILI and highlights the need for a nationwide detection and surveillance system for multiple respiratory pathogens.

Keywords: epidemiology; influenza virus; influenza-like illness (ILI); multiplex real-time polymerase chain reaction; respiratory viral pathogens.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 3
Figure 3
Monthly distribution of IFV (a) and non-IFVs (b) between 2018 and 2019.
Figure 1
Figure 1
The monthly distribution of reported ILI cases between 2018 and 2019.
Figure 2
Figure 2
The detection rate of nine respiratory viruses between 2018 and 2019. (A) Summary data for 2018 and 2019; (B) data from 2018; (C) data from 2019.
See this image and copyright information in PMC

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