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Meta-Analysis
. 2024 Feb;48(2):166-176.
doi: 10.1038/s41366-023-01412-3. Epub 2023 Nov 25.

The effects of bariatric surgery on cardiac function: a systematic review and meta-analysis

Narek Sargsyan  1 , Jun Yu Chen  2 , Ravi Aggarwal  2 , Michael G Fadel  2   3 , Matyas Fehervari  2   3 , Hutan Ashrafian  2   3
Affiliations
Meta-Analysis

The effects of bariatric surgery on cardiac function: a systematic review and meta-analysis

Narek Sargsyan et al. Int J Obes (Lond). 2024 Feb.

Abstract

Introduction: Obesity is associated with alterations in cardiac structure and haemodynamics leading to cardiovascular mortality and morbidity. Culminating evidence suggests improvement of cardiac structure and function following bariatric surgery.

Objective: To evaluate the effect of bariatric surgery on cardiac structure and function in patients before and after bariatric surgery.

Methods: Systematic review and meta-analysis of studies reporting pre- and postoperative cardiac structure and function parameters on cardiac imaging in patients undergoing bariatric surgery.

Results: Eighty studies of 3332 patients were included. Bariatric surgery is associated with a statistically significant improvement in cardiac geometry and function including a decrease of 12.2% (95% CI 0.096-0.149; p < 0.001) in left ventricular (LV) mass index, an increase of 0.155 (95% CI 0.106-0.205; p < 0.001) in E/A ratio, a decrease of 2.012 mm (95% CI 1.356-2.699; p < 0.001) in left atrial diameter, a decrease of 1.16 mm (95% CI 0.62-1.69; p < 0.001) in LV diastolic dimension, and an increase of 1.636% (95% CI 0.706-2.566; p < 0.001) in LV ejection fraction after surgery.

Conclusion: Bariatric surgery led to reverse remodelling and improvement in cardiac geometry and function driven by metabolic and haemodynamic factors.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Forest plot demonstrating changes in left ventricular mass before and after bariatric surgery.
Fig. 2
Fig. 2
Forest plot demonstrating changes in left ventricular mass index before and after bariatric surgery.
Fig. 3
Fig. 3
Forest plot demonstrating changes in left ventricular end-systolic volume before and after bariatric surgery.
Fig. 4
Fig. 4
Forest plot demonstrating changes in left ventricular end-diastolic volume before and after bariatric surgery.
Fig. 5
Fig. 5
Forest plot demonstrating changes in left ventricular global longitudinal strain before and after bariatric surgery.
Fig. 6
Fig. 6
Forest plot demonstrating changes in left ventricular diastolic dimension before and after bariatric surgery.
Fig. 7
Fig. 7
Forest plot demonstrating changes in left ventricular ejection fraction before and after bariatric surgery.
See this image and copyright information in PMC

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