Empirical decision-making for antimicrobial therapy in critically ill patients

doi:10.1016/j.bjae.2023.09.001

Review

. 2023 Dec;23(12):480-487.

doi: 10.1016/j.bjae.2023.09.001. Epub 2023 Oct 19.

Empirical decision-making for antimicrobial therapy in critically ill patients

M Ippolito^{1

2}, A Cortegiani^{1

2}

Affiliations

PMID: 38009140
PMCID: PMC10667614
DOI: 10.1016/j.bjae.2023.09.001

Review

Empirical decision-making for antimicrobial therapy in critically ill patients

M Ippolito et al. BJA Educ. 2023 Dec.

. 2023 Dec;23(12):480-487.

doi: 10.1016/j.bjae.2023.09.001. Epub 2023 Oct 19.

Authors

M Ippolito^{1

2}, A Cortegiani^{1

2}

Affiliations

¹ University of Palermo, Palermo, Italy.
² Policlinico Paolo Giaccone, Palermo, Italy.

PMID: 38009140
PMCID: PMC10667614
DOI: 10.1016/j.bjae.2023.09.001

No abstract available

Keywords: antibiotics; infections; intensive care units; sepsis.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

**Fig 1**
Mind map on the best practice for empirical antimicrobial therapy.

See this image and copyright information in PMC

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References

1. Vincent J.L., Sakr Y., Singer M., et al. Prevalence and outcomes of infection among patients in intensive care units in 2017. JAMA. 2020;323:1478–1487. - PMC - PubMed
1. Zhang D., Micek S.T., Kollef M.H. Time to appropriate antibiotic therapy is an independent determinant of postinfection ICU and hospital lengths of stay in patients with sepsis. Crit Care Med. 2015;43:2133–2140. - PubMed
1. Johnston A.N.B., Park J., Doi S.A., et al. Effect of immediate administration of antibiotics in patients with sepsis in tertiary care: a systematic review and meta-analysis. Clin Ther. 2017;39:190–202.e6. - PubMed
1. Evans L., Rhodes A., Alhazzani W., et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–1247. - PMC - PubMed
1. Szychowiak P., Villageois-Tran K., Patrier J., et al. The role of the microbiota in the management of intensive care patients. Ann Intensive Care. 2022;12:3. - PMC - PubMed

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[1] Vincent J.L., Sakr Y., Singer M., et al. Prevalence and outcomes of infection among patients in intensive care units in 2017. JAMA. 2020;323:1478–1487. - PMC - PubMed

[2] Vincent J.L., Sakr Y., Singer M., et al. Prevalence and outcomes of infection among patients in intensive care units in 2017. JAMA. 2020;323:1478–1487. - PMC - PubMed

[3] Zhang D., Micek S.T., Kollef M.H. Time to appropriate antibiotic therapy is an independent determinant of postinfection ICU and hospital lengths of stay in patients with sepsis. Crit Care Med. 2015;43:2133–2140. - PubMed

[4] Zhang D., Micek S.T., Kollef M.H. Time to appropriate antibiotic therapy is an independent determinant of postinfection ICU and hospital lengths of stay in patients with sepsis. Crit Care Med. 2015;43:2133–2140. - PubMed

[5] Johnston A.N.B., Park J., Doi S.A., et al. Effect of immediate administration of antibiotics in patients with sepsis in tertiary care: a systematic review and meta-analysis. Clin Ther. 2017;39:190–202.e6. - PubMed

[6] Johnston A.N.B., Park J., Doi S.A., et al. Effect of immediate administration of antibiotics in patients with sepsis in tertiary care: a systematic review and meta-analysis. Clin Ther. 2017;39:190–202.e6. - PubMed

[7] Evans L., Rhodes A., Alhazzani W., et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–1247. - PMC - PubMed

[8] Evans L., Rhodes A., Alhazzani W., et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–1247. - PMC - PubMed

[9] Szychowiak P., Villageois-Tran K., Patrier J., et al. The role of the microbiota in the management of intensive care patients. Ann Intensive Care. 2022;12:3. - PMC - PubMed

[10] Szychowiak P., Villageois-Tran K., Patrier J., et al. The role of the microbiota in the management of intensive care patients. Ann Intensive Care. 2022;12:3. - PMC - PubMed

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Empirical decision-making for antimicrobial therapy in critically ill patients

Affiliations

Empirical decision-making for antimicrobial therapy in critically ill patients

Authors

Affiliations

Conflict of interest statement

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