Empirical decision-making for antimicrobial therapy in critically ill patients

M Ippolito^{1

2}, A Cortegiani^{1

2}

Affiliations

Review

M Ippolito et al. BJA Educ. 2023 Dec.

. 2023 Dec;23(12):480-487.

doi: 10.1016/j.bjae.2023.09.001. Epub 2023 Oct 19.

M Ippolito^{1

2}, A Cortegiani^{1

2}

No abstract available

Keywords: antibiotics; infections; intensive care units; sepsis.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

1. Vincent J.L., Sakr Y., Singer M., et al. Prevalence and outcomes of infection among patients in intensive care units in 2017. JAMA. 2020;323:1478–1487. - PMC - PubMed
1. Zhang D., Micek S.T., Kollef M.H. Time to appropriate antibiotic therapy is an independent determinant of postinfection ICU and hospital lengths of stay in patients with sepsis. Crit Care Med. 2015;43:2133–2140. - PubMed
1. Johnston A.N.B., Park J., Doi S.A., et al. Effect of immediate administration of antibiotics in patients with sepsis in tertiary care: a systematic review and meta-analysis. Clin Ther. 2017;39:190–202.e6. - PubMed
1. Evans L., Rhodes A., Alhazzani W., et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–1247. - PMC - PubMed
1. Szychowiak P., Villageois-Tran K., Patrier J., et al. The role of the microbiota in the management of intensive care patients. Ann Intensive Care. 2022;12:3. - PMC - PubMed