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. 2023 Nov;95(11):e29255.
doi: 10.1002/jmv.29255.

An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022

Takeshi Nabeshima  1   2 , Mya Myat Ngwe Tun  1   3 , Nguyen Thi Thu Thuy  4 , Nguyen Le Khanh Hang  4 , Le Thi Quynh Mai  4 , Futoshi Hasebe  5 , Yuki Takamatsu  1   6 ; Nagasaki University Vietnam Research Group
Affiliations

An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022

Takeshi Nabeshima et al. J Med Virol. 2023 Nov.

Abstract

In 2022, a large dengue outbreak was reported in Vietnam, where dengue was endemic. A total of 1889 acute-phase serum samples were collected from patients with suspected dengue at Vung Tau General Hospital, the core hospital in Vung Tau Province, southern Vietnam. Among the 1889 samples analyzed for laboratory confirmation of dengue virus (DENV) infection, 339 positive cases were identified, of which 130 were primary infections and 209 were secondary infections. DENV-2 was the dominant serotype in both primary and secondary infection groups. Phylogenetic analysis based on sequences of the envelope protein-coding region revealed the emergence of a new DENV-2 lineage during this outbreak.

Keywords: DENV-2; Vietnam; cosmopolitan genotype; dengue; outbreak.

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References

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