Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Nov 1;33(6):839-843.
doi: 10.4103/1319-2442.390263. Epub 2023 Nov 29.

Coexistence of Interstitial Nephritis and the Cellular Variant of Focal Segmental Glomerulosclerosis Secondary to Anabolic Steroid Abuse

Abdullah Al-Hwiesh  1   2 , Khalid Al-Amoudi  1   2 , Khadija Alshehabi  1   2 , Muaz Abdelgalil  1   2 , Bardan Al-Hwiesh  1   2 , Amani Alhwiesh  1   2 , Nadia Al-Audah  3 , Sana M Al Solami  3 , Wael Mostafa Hamza  2   4 , Ibrahiem Saeed Abdul-Rahman  1
Affiliations
Free article
Case Reports

Coexistence of Interstitial Nephritis and the Cellular Variant of Focal Segmental Glomerulosclerosis Secondary to Anabolic Steroid Abuse

Abdullah Al-Hwiesh et al. Saudi J Kidney Dis Transpl. .
Free article

Abstract

Anabolic-androgenic steroids (AAS) have been widely used by young people to enhance performance and increase muscle mass. The use of AAS can affect the kidneys and lead to a myriad of presentations, ranging from mildly elevated serum creatinine and blood urea nitrogen to irreversible chronic kidney disease and focal segmental glomerulosclerosis (FSGS). To the best of our knowledge, the coexistence of interstitial nephritis and the cellular variant of FSGS [Immunoglobulin M (IgM)] secondary to AAS abuse has not been previously reported in the literature. Here, we report the case of a 40-year-old bodybuilder who developed simultaneous interstitial nephritis and the cellular variant of FSGS (IgM) after short-term use of AAS and other dietary supplements.

PubMed Disclaimer

References

    1. Bird SR, Goebel C, Burke LM, Greaves RF. Doping in sport and exercise: Anabolic, ergogenic, health and clinical issues. Ann Clin Biochem 2016;53:196-221.
    1. Shahidi NT. A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids. Clin Ther 2001;23:1355-90.
    1. Sjöqvist F, Garle M, Rane A. Use of doping agents, particularly anabolic steroids, in sports and society. Lancet 2008;371:1872-82.
    1. Sagoe D, Molde H, Andreassen CS, Torsheim T, Pallesen S. The global epidemiology of anabolic-androgenic steroid use: A metaanalysis and meta-regression analysis. Ann Epidemiol 2014;24:383-98.
    1. Goldman A, Basaria S. Adverse health effects of androgen use. Mol Cell Endocrinol 2018;464:46-55.

Publication types

MeSH terms

LinkOut - more resources