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. 2023 Nov 30;62(5):e110-e112.
doi: 10.1515/cclm-2023-1196. Print 2024 Apr 25.

What could cause a false increase in serum C-reactive protein concentration?

Affiliations

What could cause a false increase in serum C-reactive protein concentration?

Mélanie Bouillon et al. Clin Chem Lab Med. .
No abstract available

Keywords: C-reactive protein; heterophile antibody; immunoassay; interference.

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References

    1. Tiwari, V, Jandu, JS, Bergman, MJ. Rheumatoid factor ; 2023.
    1. Bjerner, J, Børmer, OP, Nustad, K. The war on heterophilic antibody interference. Clin Chem 2005;51:9–11. https://doi.org/10.1373/clinchem.2004.042994 . - DOI
    1. Schnebelen, A, Sweat, K, Marshall, J, Bornhorst, J. Alleviation of IgM monoclonal protein interference in nephelometric assays by sample treatment with reducing agent in a chaotropic salt solution: table 1. Am J Clin Pathol 2012;137:26–8. https://doi.org/10.1309/AJCPUXD1WI2HJDMO . - DOI
    1. Tate, J, Ward, G. Interferences in immunoassay. Clin Biochem Rev 2004;25:105–20.
    1. Fishman, JB, Berg, EA. Protein A and protein G purification of antibodies. Cold Spring Harb Protoc 2019;2019:82–4. https://doi.org/10.1101/pdb.prot099143 . - DOI

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