Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Aug 31:45:193.
doi: 10.11604/pamj.2023.45.193.5325. eCollection 2023.

Laryngeal tuberculosis: about 04 cases

Affiliations
Case Reports

Laryngeal tuberculosis: about 04 cases

Abdelilah Mouhsine et al. Pan Afr Med J. .

Abstract

The purpose of this study is to present epidemiological, clinical, radiological, histological characteristics and treatment of laryngeal tuberculosis. It is also aimed at making the point about diagnosis difficulties. This retrospective study was conducted over three years; it concerned 4 cases, 3 males and one female. The average age was 35 years. Three of the 4 cases have had a cervical CT scan. All patients have had a laryngoscopy with biopsy and anatomopathological study. The onset modes of the disease have been progressive for all the patients. Topographical study has shown two epiglottic locations, one at the vocal cords and the other one at the posterior commissure. The diagnosis was orientated in the 3 cases by the CT scan and confirmed by anatomopathological exam in all cases. All patients have received anti-TB drugs with good evolution. The laryngeal location of tuberculosis is unusual. The clinical picture is nonspecific, raising the issue of differential diagnosis with tumor pathology. Sectional imaging and CT scan can guide the diagnosis and a positive diagnosis is often discovered on the occasion of a tumor biopsy of a pseudo-tumor lesion. Treatment is based on anti-TB drugs.

Keywords: Tuberculosis; anti-TB drugs; ear; extra nodal; larynx; nose and throat.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
chest radiograph showing reticulo nodular infiltrate of the right apex
Figure 2
Figure 2
front reconstruction image of laryngeal CT scan objectifying the presence of a thickening, heterogeneous tissue of the left supra glottic laryngeal stage reaching lateral glosso epiglottic ligament and ipsilateral vallicula sidewall
Figure 3
Figure 3
laryngeal CT axial section after injection of contrast material objectifying the presence of a thickening, heterogeneous tissue of the left supra glottic laryngeal stage reaching lateral glosso epiglottic ligament and ipsilateral vallicula sidewall
Figure 4
Figure 4
laryngeal CT axial section after injection of contrast objectifying a filling of the left ventricle with collapse of the ipsilateral piriform sinus
Figure 5
Figure 5
pseudo tumor form of laryngeal tuberculosis
Figure 6
Figure 6
histological sample showing a nasopharyngeal mucosa subject to a granuloma giant with epithelioid cells caseating confirming active tuberculosis

References

    1. Ahmed ID I, Hammi S, Jahnaoui N, Asri N, Marc K, Soualhi M, et al. La tuberculose extra ganglionnaire de la sphère ORL. Revue des maladies respiratoires. 2012 Janvier;29(S1):A12.
    1. El Ayoubi A, Benhammou A, El Ayoubi F, El Fahssi A, Nitassi S, Kohen A, et al. La tuberculose primitive ORL extra ganglionnaire. Annales d´OtoLaryngologie et de chirurgie cervico faciale. 2009 Septembre;126(4):208–215. - PubMed
    1. Bouaity B, et al. Tuberculose du naso-pharynx: à propos d'un cas. Lettre d'ORL et de chirurgie cervico-faciale. 2009;319:14–16.
    1. Kossowski M, Conessa C, Clement P, Roguet E, Verdalle P, Poncet GL. Aspects actuels de la tuberculose laryngée: à propos de 4 cas. Ann Otolaryngol chir cervicofac. 2002;119:281–286. - PubMed
    1. Kandileros DC, Nicolopoulos TP, Ferekidis E, Tsangaroulakis A, Yiotakis JE, Davilis D, et al. Laryngeal tuberculosis at the end of the 20th century. J Laryngol Otol. 1997;111:619–21. - PubMed

Publication types