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Case Reports
. 2023 Oct 9;15(10):e46724.
doi: 10.7759/cureus.46724. eCollection 2023 Oct.

Hepatic Glucagonoma in a Post-bariatric Female Patient: A Case Report

Sophia Garcia  1 , Saly J Canela Ynoa  2 , Arturo M Concepción  1 , Flávio A De Sá Ribeiro  1
Affiliations
Case Reports

Hepatic Glucagonoma in a Post-bariatric Female Patient: A Case Report

Sophia Garcia et al. Cureus. .

Abstract

Glucagonomas, neuroendocrine tumors originating from the pancreas marked by excessive glucagon secretion, present a diagnostic challenge due to their rarity and diverse symptomatology. In this report, we present a 47-year-old female with a history of bariatric surgery, diabetes mellitus, and deep vein thrombosis who exhibited weight loss, anemia, migratory necrolytic erythema on the lower limbs and groin, and fecal incontinence. Imaging revealed liver secondary lesions without an identifiable primary tumor. After undergoing surgery, a pathologic examination of the excised tissue confirmed that the lesions were a glucagonoma. This case underscores the imperative of how common side effects of bariatric surgery could mask symptoms, delaying the diagnosis of glucagonomas.

Keywords: diabetes mellitus; general surgery; glucogonoma; necrolytic migratory erythema; neuroendocrine tumor.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. CT at Admission
The red arrow shows the main hepatic lesion.
Figure 2
Figure 2. Patient's Migratory Necrolytic Erythema
The picture shows the groin region of the patient; the red arrow highlights where erythema is evident.
Figure 3
Figure 3. Excised Tissue
Segment IVa of the liver
Figure 4
Figure 4. Excised Tissue
Segments II and III of the liver
Figure 5
Figure 5. Microscopy of the Excised Tissue
The image shows a neuroendocrine tumor
Figure 6
Figure 6. Post-surgical Computed Tomography
The red arrow shows segment IVb
See this image and copyright information in PMC

References

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