Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 13:10:23743735231211069.
doi: 10.1177/23743735231211069. eCollection 2023.

The Impact of Living With Chronic Hepatitis B on Quality of Life: Implications for Clinical Management

Yasmin Ibrahim  1 , Madeleine Umstead  1 , Su Wang  2   3 , Chari Cohen  1
Affiliations

The Impact of Living With Chronic Hepatitis B on Quality of Life: Implications for Clinical Management

Yasmin Ibrahim et al. J Patient Exp. .

Abstract

Living with chronic hepatitis B (CHB) has physical, social, and emotional impacts that often negatively affect patients' quality of life. These impacts are not usually captured during routine care. This article presents information on the impact of living with CHB and the importance of integrating health-related quality-of-life assessment into CHB care. Using a global online survey, people ages ≥18 living with CHB were asked about physical, social, and worry impacts. Of 1707 respondents, most were male (67%), < 45 years of age (81%); and 52% identified as Black. Of all participants, 66% reported physical impact, 55% reported social impact, and 49% reported worry impact of living with CHB. Those from Africa and the Western Pacific were most likely to report physical impact. Younger participants (18-45) and those not on treatment were significantly more likely to report physical and social impact. People living with CHB are impacted physically, socially, and emotionally, varied by demographic factors and disease experience. These impacts should be captured and addressed as part of routine CHB care.

Keywords: chronic hepatitis B; health-related quality of life; patient-reported outcomes (PROs); physical impact; social impact; worry impact.

PubMed Disclaimer

References

    1. GBD 2019 Hepatitis B Collaborators. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet Gastroenterol Hepatol, 2022;7(9):796-829. doi: 10.1016/S2468-1253(22)00124-8 - DOI - PMC - PubMed
    1. Bruix J, Sherman M. American association for the study of liver disease. Management of hepatocellular carcinoma: an update. Hepatology. 2011. Mar;53(3):1020-2. doi: 10.1002/hep.24199 - DOI - PMC - PubMed
    1. European Association For The Study Of The Liver, European Organization For Research. Treatment of cancer. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol. 2012. Apr;56(4):908-43. doi: 10.1016/j.jhep.2011.12.001 - PubMed
    1. Lok AS, McMahon BJ, Brown RS, Jr, et al. Antiviral therapy for chronic hepatitis B viral infection in adults: a systematic review and meta-analysis. Hepatology. 2016;63(1):284-306. doi: 10.1002/hep.28280 - DOI - PubMed
    1. Ahmed Si N, Ecochard M, Zoulim F. End points of therapy in chronic hepatitis B. Expert Rev Gastroenterol Hepatol. 2010;4(1):37-49. doi: 10.1586/egh.09.65 - DOI - PubMed

LinkOut - more resources